Department of Pediatrics, University of Chieti, I - 66100 Chieti, Italy.
Diabetes Metab Res Rev. 2009 Sep;25 Suppl 1:S34-44. doi: 10.1002/dmrr.986.
Diabetes mellitus is the most common endocrine disease in childhood and adolescence. Type 1 diabetes accounts for over 90% of diabetes in children. During the past decades, epidemiological studies have clearly shown a worldwide increase in the incidence of both type 1 and type 2 diabetes in many countries. The worldwide incidence of diabetes and especially the diabetes-related complications highlight the relevant economic burden of this disease. In fact, its costs affect health services, national productivity as well as individuals and families. Hospital in-patient costs for the treatment of complications are the largest single contributor to direct healthcare costs. Anyway, many of these complications and, therefore, their costs, as well as most of the indirect costs, are partially or completely preventable. In fact, intensive therapy, directed at controlling blood glucose, blood pressure and lipid levels, has been shown to be cost effective in that, although initial costs are high, longer term costs decrease as a result of delayed or prevented complications. From this point of view, technological advances have provided new therapeutic options to achieve metabolic control as close to normal as possible in children and adolescents with diabetes. In fact, the relevant technological devices that have been adopted till now, if adequately utilized, should allow patients to achieve intensive management with improved metabolic control, quality of life as well as reduced mortality and morbidity. However, new technologies are not a panacea, and the benefit they provide can be completely achieved only if adequately and especially individually determined. Furthermore, it is inevitable that new modalities of treatment for people with diabetes will be considered critically by healthcare planners and providers in the prevailing global environment of increasing costs of medical care and pressure for rational allocation of resources. Therefore, new technologically derived devices and therapeutic opportunity for diabetes should be rationally utilized in order to offer real advantages and reduce the relevant worldwide cost of diabetes.
糖尿病是儿童和青少年中最常见的内分泌疾病。1 型糖尿病占儿童糖尿病的 90%以上。在过去的几十年中,流行病学研究清楚地表明,在许多国家,1 型和 2 型糖尿病的发病率都在全球范围内增加。糖尿病的全球发病率,尤其是与糖尿病相关的并发症,突显了这种疾病的相关经济负担。事实上,其成本影响医疗服务、国家生产力以及个人和家庭。治疗并发症的住院患者费用是直接医疗保健成本的最大单一贡献者。无论如何,这些并发症中的许多,以及因此产生的成本,以及大多数间接成本,部分或完全是可以预防的。事实上,强化治疗,旨在控制血糖、血压和血脂水平,已被证明具有成本效益,因为尽管初始成本较高,但由于并发症的延迟或预防,长期成本会降低。从这个角度来看,技术进步为儿童和青少年糖尿病患者提供了新的治疗选择,使他们尽可能接近正常的代谢控制。事实上,迄今为止采用的相关技术设备,如果得到充分利用,应该可以使患者通过强化管理实现更好的代谢控制、提高生活质量以及降低死亡率和发病率。然而,新技术并不是万能的,只有在充分且特别是个别确定的情况下,才能完全实现它们所提供的益处。此外,在医疗保健成本不断增加和资源合理配置压力的全球环境下,糖尿病患者的新治疗方法不可避免地会受到医疗保健规划者和提供者的严格审查。因此,应该合理利用新的技术衍生设备和治疗糖尿病的机会,以提供真正的优势并降低全球范围内糖尿病的相关成本。