Liu Xin-yue, Chen Kai-lan, You Yong, Chen Wan-xin, Zou Ping
Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
Zhonghua Nei Ke Za Zhi. 2005 Dec;44(12):902-5.
To facilitate the diagnosis of histoplasmosis, kala-azar, penicilliosis marneffei, toxoplasmosis and cryptococcosis with the help of bone marrow morphology.
The clinical features and bone marrow cytomorphology in 7 cases of histoplasmosis, 1 case of kela-azar, 1 case of penicilliosis marneffei, 2 cases of toxoplasmosis and 3 cases of cryptococcosis were studied.
In the bone marrow examination, the form of histoplasma capsule was ovoid with a colorless circle. The morphology of Leishmania donovani was similar to that of histoplasma capsule except that there were terkinetoplasts present in the former. Sausage form and central cross wall were signs of Penicillium marneffei. Toxoplasma gondii looked like a banana and cryptococcus neoformans was larger than the others and had a thick capsule.
The examination of bone marrow is important to the diagnosis of these rare infectious diseases.
借助骨髓形态学促进组织胞浆菌病、黑热病、马尔尼菲青霉病、弓形虫病和隐球菌病的诊断。
对7例组织胞浆菌病、1例黑热病、1例马尔尼菲青霉病、2例弓形虫病和3例隐球菌病患者的临床特征及骨髓细胞形态进行研究。
骨髓检查中，荚膜组织胞浆菌形态为卵圆形，有一无色圈。杜氏利什曼原虫形态与荚膜组织胞浆菌相似，但前者有动基体。腊肠形及中央横壁是马尔尼菲青霉的特征。刚地弓形虫形似香蕉，新型隐球菌比其他病原体大且有厚荚膜。
骨髓检查对这些罕见传染病的诊断具有重要意义。
