Hou Xiao-tong, Meng Xu, Li Wei, Wang Jian-gang
Department of Cardiac Surgery, Beijing An Zhen Hospital, Capital University of Medical Science, Beijing 100029, China.
Zhonghua Yi Xue Za Zhi. 2005 Dec 14;85(47):3362-4.
To investigate the appropriate methodology and outcome of surgical treatment of tricuspid regurgitation late after valve replacement of left heart.
Eighteen patients with tricuspid insufficiency, with the diagnosis conformed by echocardiogram and in New York Heart Association (NYHA) class III to IV, were treated surgically 3 to 14 years after left heart valve replacement, including 13 mitral valve replacements and 5 double valve replacements, from January 1995 to May 2004. DeVega was used in 5 patients. The ages at the time of tricuspid surgery ranged from 35 to 65 years (median 50 years). The patients were followed up for 36.7 months (12-114 months).
There was no death from hemorrhage because of re-open. Tricuspid repair was performed in 8 patients, tricuspid replacement was done in 10 patients, 5 bioprostheses and 5 mechanical valves were implanted. The hospital mortality was 16.7%. Among the survivors, the three-year survival rate was 78.8%. Twelve patients showed improvement of symptoms, while there was no improvement in 3 patients who needed medical therapy.
The pathophysiology of tricuspid regurgitation is associated with delayed left heart operation, implement of tricuspid repair in the first operation or progressive right ventricular failure. The surgical intervention should be earlier before the onset of severe right ventricular failure Tricuspid valve repair is the procedure of choice, while tricuspid valve replacement is also acceptable.
探讨左心瓣膜置换术后晚期三尖瓣反流的合适手术方法及疗效。
1995年1月至2004年5月,18例经超声心动图确诊为三尖瓣关闭不全、纽约心脏协会(NYHA)心功能分级为Ⅲ至Ⅳ级的患者,在左心瓣膜置换术后3至14年接受手术治疗,其中二尖瓣置换术13例,双瓣膜置换术5例。5例患者采用DeVega术。三尖瓣手术时年龄35至65岁(中位年龄50岁)。患者随访36.7个月(12至114个月)。
无因再次开胸导致的出血死亡。8例患者行三尖瓣修复术,10例患者行三尖瓣置换术,植入生物瓣膜5个,机械瓣膜5个。医院死亡率为16.7%。存活患者中,三年生存率为78.8%。12例患者症状改善,3例需药物治疗的患者症状无改善。
三尖瓣反流的病理生理与左心手术延迟、首次手术时三尖瓣修复的实施或进行性右心室衰竭有关。手术干预应在严重右心室衰竭发作前尽早进行。三尖瓣修复是首选术式,三尖瓣置换也可接受。