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用曲安奈德检测患有星状玻璃体病变的眼睛中的玻璃体黄斑粘连。

Detecting vitreomacular adhesions in eyes with asteroid hyalosis with triamcinolone acetonide.

作者信息

Yamaguchi Takefumi, Inoue Makoto, Ishida Susumu, Shinoda Kei

机构信息

Department of Ophthalmology, Keio University, School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo, 160-8582, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2007 Feb;245(2):305-8. doi: 10.1007/s00417-005-0236-8.

Abstract

BACKGROUND

To report the incidence of posterior vitreous detachments (PVDs) and the surgical results of vitrectomy with intravitreal triamcinolone acetonide (TA) to detect vitreomacular adhesions in eyes with asteroid hyalosis (AH).

METHODS

Ten eyes of nine patients with AH underwent vitrectomy, six eyes with TA and four without TA. The presence of a PVD was determined preoperatively by ultrasound echography (USE) and intraoperatively by microscopic observations. The postoperative best-corrected visual acuities (BCVA) were evaluated.

RESULTS

The BCVA was improved by >2 Snellen lines in nine eyes and maintained at 20/20 with symptomatic improvements in the other eye. A vitreomacular adhesion was clearly seen during TA-assisted vitrectomy, and none was seen when TA was not used, even though preoperative USE showed an incomplete PVD in all eyes. The BCVA was not significantly better in eyes with TA-assisted vitrectomy than without TA-assisted vitrectomy. In one eye with vitrectomy without TA, a second surgery was required for a persistent cystoid macular edema and an epiretinal membrane. The BCVA and the edema in this eye improved after removing the epiretinal membrane.

CONCLUSIONS

All (ten) of the eyes with AH were found to have a vitreomacular adhesion by preoperative USE and intraoperative microscopic observations. The residual vitreous over the macula is more easily detected and removed after intravitreally injected TA, but the visual acuities were not significantly different from eyes without TA.

摘要

背景

报告后玻璃体脱离(PVD)的发生率以及玻璃体腔内注射曲安奈德(TA)进行玻璃体切割术以检测星状玻璃体病变(AH)患眼玻璃体黄斑粘连的手术结果。

方法

9例AH患者的10只眼接受了玻璃体切割术,其中6只眼注射了TA,4只眼未注射TA。术前通过超声检查(USE)和术中通过显微镜观察确定是否存在PVD。评估术后最佳矫正视力(BCVA)。

结果

9只眼的BCVA提高了>2行Snellen视力表视力,另一只眼的视力维持在20/20,症状有所改善。在TA辅助玻璃体切割术中清楚地看到了玻璃体黄斑粘连,而未使用TA时未观察到粘连,尽管术前USE显示所有患眼均存在不完全PVD。TA辅助玻璃体切割术患眼的BCVA并不比未进行TA辅助玻璃体切割术的患眼明显更好。在一只未注射TA的玻璃体切割术患眼中,因持续性黄斑囊样水肿和视网膜前膜需要进行二次手术。切除视网膜前膜后,该眼的BCVA和水肿情况有所改善。

结论

通过术前USE和术中显微镜观察发现,所有(10只)AH患眼均存在玻璃体黄斑粘连。玻璃体腔内注射TA后,黄斑区残留的玻璃体更容易被检测到并清除,但视力与未注射TA的患眼相比无显著差异。

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