拉莫三嗪在舌咽神经痛中的应用：一例报告

Use of lamotrigine in glossopharyngeal neuralgia: a case report.

作者信息

Titlic Marina, Jukic Ivana, Tonkic Ante, Grani Paula, Jukic Jelena

出版信息

Headache. 2006 Jan;46(1):167-9. doi: 10.1111/j.1526-4610.2006.00316_2.x.

DOI:10.1111/j.1526-4610.2006.00316_2.x

Abstract

We describe a case of a patient with glossopharyngeal neuralgia (refractory to treatment with carbamazepine, amytriptyline, diazepam, and indomethacin) treated with lamotrigine as monotherapy, the first described, who responded completely to the therapy and did not complain of side effects. The complete analgesic effect was reached at the lamotrigine daily dose of 200 mg per day and was maintained at that dose for additional 6 months, with the blood concentration within the reference range.

摘要

我们描述了一例患有舌咽神经痛的患者（对卡马西平、阿米替林、地西泮和吲哚美辛治疗无效），该患者接受拉莫三嗪单一疗法治疗，这是首例此类报道，患者对该疗法完全有效且未出现副作用。在拉莫三嗪每日剂量为200毫克时达到完全镇痛效果，并在该剂量下维持了6个月，血药浓度在参考范围内。