Holstege Frank C P, Clevers Hans
Department of Physiological Chemistry, University Medical Center Utrecht, 3584 CG Utrecht, the Netherlands.
Cell. 2006 Jan 13;124(1):21-3. doi: 10.1016/j.cell.2005.12.026.
In this issue of Cell, Hallikas et al. (2006) and Wei et al. (2006) describe different ways of identifying direct targets of transcription factors and their corresponding regulatory sequences in the genome. Although still under development, these studies provide an efficient way to decipher regulatory networks.
在本期《细胞》杂志中,哈利卡斯等人(2006年)和魏等人(2006年)描述了在基因组中识别转录因子直接靶标及其相应调控序列的不同方法。尽管仍在发展之中,但这些研究提供了一种破译调控网络的有效方法。