Braga M
Istituto di Statistica Medica e Biometria, Milan, Italy.
Sci Total Environ. 1992 Jun 9;120(1-2):173-84. doi: 10.1016/0048-9697(92)90229-l.
Healy's non-parametric method, originally applied to growth data, provides an efficient and flexible tool for computing smoothed centile curves. We used this procedure to calculate reference curves for blood lead levels. A sample of 402 blood donors living in Brescia and its surrounding area was used as a reference population. No exclusion criteria but occupational exposure to lead were adopted. The comparison between the reference values obtained with Healy's procedure and the tolerance limits, based on the normal approximation, computed within age strata is discussed.
希利的非参数方法最初应用于生长数据，为计算平滑百分位数曲线提供了一种高效且灵活的工具。我们使用此程序来计算血铅水平的参考曲线。选取了居住在布雷西亚及其周边地区的402名献血者作为参考人群。除职业性铅暴露外，未采用其他排除标准。文中讨论了用希利程序获得的参考值与基于正态近似在年龄分层内计算出的耐受限度之间的比较。
