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HIV相关性面部脂肪萎缩:病因及治疗选择

HIV facial lipoatrophy: causes and treatment options.

作者信息

Jones Derek

机构信息

Division of Dermatology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California, USA.

出版信息

Dermatol Surg. 2005 Nov;31(11 Pt 2):1519-29; discussion 1529. doi: 10.2310/6350.2005.31237.

DOI:10.2310/6350.2005.31237
PMID:16416634
Abstract

BACKGROUND

Human immunodeficiency virus (HIV)-associated facial lipoatrophy is becoming epidemic and may seriously affect quality of life.

OBJECTIVE

To review the possible causes and treatment options for HIV facial lipoatrophy.

METHODS

This article is based on a review of the medical literature and the author's clinical experience in treating HIV facial

CONCLUSION

Although absorbable injectable fillers and implants are helpful in treating HIV facial lipoatrophy, they are limited by cost and the short duration of correction. Newer forms of longer-lasting fillers (poly-L-lactic acid [Sculptra]) and permanent injectable fillers (liquid injectable silicone) are proving useful for treatment of this condition.

摘要

背景

人类免疫缺陷病毒(HIV)相关的面部脂肪萎缩正在流行,可能严重影响生活质量。

目的

综述HIV面部脂肪萎缩的可能病因及治疗选择。

方法

本文基于对医学文献的综述以及作者治疗HIV面部疾病的临床经验。

结论

尽管可吸收注射填充剂和植入物有助于治疗HIV面部脂肪萎缩,但它们受到成本和矫正持续时间短的限制。新型的长效填充剂(聚左旋乳酸[Sculptra])和永久性注射填充剂(液体注射硅酮)已被证明对治疗这种疾病有用。

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