Lialios Georgios, Kallitsaris Athanasios, Bourantas Konstantinos L, Messinis Ioannis E
Department of Obstetrics and Gynecology, Medical School, University of Thessalia, Greece.
J Reprod Med. 2005 Nov;50(11):863-6.
Women carrying triplets are at greater risk for both anemia, due to the increased demands of the developingfetuses, and peripartum hemorrhage. Jehovah's witnesses are a unique obstetric population since women of this faith refuse blood transfusion.
A Jehovah's Witness with a triplet pregnancy was successfully administered recombinant human erythropoietin (rHuEpo), 200 IU/kg 3 times per week subcutaneously, in order to correct her peripartum anemia. No side effects were observed during rHuEpo therapy, and the patient delivered healthy triplets.
rHuEpo can be safely administered, with a beneficial effect in pregnancy, and seems to be an effective option in preventing transfusions as demonstrated in this case in a Jehovah's Witness.
由于发育中的胎儿需求增加,怀有三胞胎的女性患贫血和围产期出血的风险更高。耶和华见证人教派是一个独特的产科群体,因为该教派的女性拒绝输血。
一名怀有三胞胎的耶和华见证人教派女性成功接受了重组人促红细胞生成素(rHuEpo)治疗,每周皮下注射3次,每次200 IU/kg,以纠正其围产期贫血。在rHuEpo治疗期间未观察到副作用,患者顺利产下健康的三胞胎。
rHuEpo可以安全给药,对妊娠有有益作用,并且似乎是预防输血的有效选择,如本病例中一名耶和华见证人教派女性的情况所示。