Tarassov Kirill, Michnick Stephen W
Département de Biochimie and Centre Robert-Cedergren, Bioinformatiques et Genomiques, Université de Montréal, CP 6128, Succursale Centre-ville, Montréal, Québec, H3C 3J7, Canada.
Genome Biol. 2005;6(13):R115. doi: 10.1186/gb-2005-6-13-r115. Epub 2005 Dec 30.
We have developed an application, iVici, to analyze cellular networks represented as addressable symmetric or asymmetric two-dimensional matrices. iVici was designed to permit simultaneous visualization and correlation of multiple datasets, representing any relationship between a set of genes, mRNAs, or proteins. Visual overlay of datasets and addressable access to gene annotations permits comparison of networks of different types (for example protein-protein interactions and genetic networks) or investigation of the dynamic reorganization of a particular network.
我们开发了一款名为iVici的应用程序,用于分析以可寻址对称或不对称二维矩阵表示的细胞网络。iVici旨在允许同时可视化和关联多个数据集,这些数据集代表一组基因、mRNA或蛋白质之间的任何关系。数据集的可视化叠加以及对基因注释的可寻址访问,使得能够比较不同类型的网络(例如蛋白质-蛋白质相互作用网络和遗传网络),或者研究特定网络的动态重组。