Luo Erping, Jiao Licheng, Shen Guanghao, Wu Xiao-Ming, Xu Qiaoling, Lu Lihua
Research Center of Intelligent Information Processing, School of Electronic Engineering, Xidian University, Xi'an 710071, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2005 Dec;22(6):1168-70.
The effects of the pulsed electromagnetic fields (PEMFs) of different intensity on bone mineral density (BMD) and biomechanical properties of rabbits' femur had been studied. Twenty-seven female white big ear rabbits were randomly divided into three groups. The magnetic groups were fed in 15 Hz PEMFs, which pulse duration was set to be 5 ms (6 h x d(-1)), the magnetic intensity was 10 x 10(-4) T and the other was 20 x 10(-4) T. Control group were just fed in coils, and the instrument of PEMFs was powered off. After six weeks, by examine BMD and biomechanical properties of the rabbits' femur, the effects of these PEMFs were studied. Compared with control group, the values of BMD, maximum load and structural rigidity of magnetic group were significantly increased (P < 0.05). In addition, there was significant increase in values of BMD and structural rigidity in group 10 x 10(-4) T in comparison with group 20 x 10(-4) T (P < 0.05). PEMFs is effective in improving BMD and biomechanical properties. The experiment indicated that there was evident "window-effect" during the treatment by PEMFs. It is favorable to the treatment and prevention of osteoporosis.
研究了不同强度的脉冲电磁场（PEMFs）对兔股骨骨密度（BMD）和生物力学性能的影响。将27只雌性白色大耳兔随机分为三组。磁场组在15Hz的PEMFs中饲养，脉冲持续时间设定为5ms（6h·d⁻¹），磁场强度分别为10×10⁻⁴T和20×10⁻⁴T。对照组仅在线圈中饲养，PEMFs仪器关闭。六周后，通过检测兔股骨的BMD和生物力学性能，研究了这些PEMFs的作用。与对照组相比，磁场组的BMD、最大负荷和结构刚度值显著增加（P<0.05）。此外，10×10⁻⁴T组的BMD和结构刚度值与20×10⁻⁴T组相比显著增加（P<0.05）。PEMFs对改善BMD和生物力学性能有效。实验表明，PEMFs治疗期间存在明显的“窗口效应”。这有利于骨质疏松症的治疗和预防。
