Liem A T, Keunen J E, van Norren D
F. C. Donders Institute of Ophthalmology, University Hospital, Utrecht, The Netherlands.
Am J Ophthalmol. 1992 Aug 15;114(2):149-57. doi: 10.1016/s0002-9394(14)73978-9.
We compared the results of foveal densitometry with results of other retinal function tests in five asymptomatic subjects with adult-onset diffuse drusen. All results of routine retinal function tests, including visual acuity, Rayleigh equation color matches, multiple static perimetry, electroretinography, and electro-oculography, were normal. All five subjects had decreased foveal cone photopigment density with densitometry, indicating an early dysfunction at the level of the foveal cone photoreceptors. Several functional defects may be responsible for the densitometric results in adult-onset diffuse drusen, including retinal pigment epithelium dysfunction, foveal cone photoreceptor misalignment, and a reduction of the in situ foveal cone photopigment.
我们比较了五名患有成人起病性弥漫性玻璃膜疣的无症状受试者的中央凹密度测定结果与其他视网膜功能测试结果。所有常规视网膜功能测试结果均正常，包括视力、瑞利方程颜色匹配、多次静态视野检查、视网膜电图和眼电图。通过密度测定，所有五名受试者的中央凹视锥光色素密度均降低，表明中央凹视锥光感受器水平存在早期功能障碍。成人起病性弥漫性玻璃膜疣的密度测定结果可能由多种功能缺陷导致，包括视网膜色素上皮功能障碍、中央凹视锥光感受器排列不齐以及中央凹视锥光色素原位减少。
