Daube Jasper R
Mayo Clinic Department of Neurology, 200 First Street SW, E8B, Rochester, MN 55905-0001, USA.
J Neurol Sci. 2006 Mar 15;242(1-2):23-35. doi: 10.1016/j.jns.2005.11.011. Epub 2006 Jan 19.
Quantitation has become an increasingly important part of clinical EMG. Most aspects of peripheral nerve and muscle function can be evaluated quantitatively using commonly available neurophysiologic methods. Because of the effects of collateral sprouting and reinnervation, techniques to measure the number of motor units supplying a muscle have been more difficult to develop. Motor unit number estimation (MUNE) consists of a number of different methods that evaluate the last unmeasured variable in nerve disease. The various MUNE techniques and their common technical issues will be reviewed, and potential clinical and research applications emphasized.
定量分析已成为临床肌电图中日益重要的一部分。使用常见的神经生理学方法可以对外周神经和肌肉功能的大多数方面进行定量评估。由于侧支芽生和再支配的影响，测量支配一块肌肉的运动单位数量的技术一直较难开发。运动单位数量估计（MUNE）由多种不同方法组成，这些方法用于评估神经疾病中最后一个未测量的变量。将对各种MUNE技术及其常见技术问题进行综述，并强调其潜在的临床和研究应用。
