Varin O C, Varin D S E, Houben G M P, de Hemptinne B
Universitair Ziekenhuis Gent, vakgroep Heelkunde, De Pintelaan 185, 9000 Gent, België.
Ned Tijdschr Geneeskd. 2005 Dec 31;149(53):2979-81.
In a 66-year-old woman with pruritus, jaundice, dark-brown urine and light-colored faeces obstructive jaundice was diagnosed. Despite extensive investigations, it was not possible to clearly distinguish if varicosis or cholangiocarcinoma was the cause of the obstruction. During laparotomy the right lobe of the liver was seen to be greatly underdeveloped. The portal system showed a varicose deformation with compression of the bile ducts and portal hypertension. The right lobe of the liver was removed and the portal hypertension was treated by creating a shunt between the hepatic portal vein and the right ovarian vein. The jaundice disappeared and the patient recovered. Histological investigation showed atrophy, secondary biliary fibrosis, cirrhosis and a biliary cystadenoma. There were no signs of malignancy. The varicose deformation can be considered to be a result of the portal hypertension caused by fibrosis and cirrhosis with possibly a history of thrombosis and insufficient recanalization.
在一名66岁患有瘙痒、黄疸、深褐色尿液和浅色粪便的女性患者中,诊断为梗阻性黄疸。尽管进行了广泛的检查,但仍无法明确区分静脉曲张或胆管癌是否为梗阻原因。剖腹手术时发现肝脏右叶发育严重不良。门静脉系统呈现静脉曲张变形,压迫胆管并导致门静脉高压。切除肝脏右叶,并通过在肝门静脉和右卵巢静脉之间建立分流来治疗门静脉高压。黄疸消失,患者康复。组织学检查显示萎缩、继发性胆汁性纤维化、肝硬化和胆管囊腺瘤。无恶性迹象。静脉曲张变形可被认为是由纤维化和肝硬化引起的门静脉高压的结果,可能有血栓形成史且再通不足。