Brown Kevin K
Chest. 2006 Jan;129(1 Suppl):132S-137S. doi: 10.1378/chest.129.1_suppl.132S.
To review the role of nonbronchiectatic suppurative airway disease (bronchiolitis) in the spectrum of causes of cough and its management.
DESIGN/METHODOLOGY: A MEDLINE search (through May 2004) for studies published in the English language since 1980 on human subjects using the medical subject heading terms "cough," "causes of cough," "etiology of cough," "interstitial lung disease," "bronchiolitis," "bronchiolitis obliterans," "diffuse panbronchiolitis," and "inflammatory bowel disease" was performed. Case series and prospective descriptive clinical trials were selected for review. Any references from these studies that were pertinent to the topic were also obtained.
RESULTS/CONCLUSIONS: In patients with cough in whom other more common causes of cough have been excluded, incomplete or irreversible airflow limitation, small airways disease seen on high-resolution CT scan, or purulent secretions seen on bronchoscopy, should suggest nonbronchiectatic suppurative airways disease (bronchiolitis) as a potential primary cause. Successful management depends on the identification of the specific underlying disorder.
回顾非支气管扩张性化脓性气道疾病（细支气管炎）在咳嗽病因谱中的作用及其管理。
设计/方法：使用医学主题词“咳嗽”“咳嗽病因”“咳嗽的病因学”“间质性肺疾病”“细支气管炎”“闭塞性细支气管炎”“弥漫性泛细支气管炎”和“炎症性肠病”，对1980年以来以英文发表的关于人类受试者的研究进行MEDLINE检索（截至2004年5月）。选择病例系列和前瞻性描述性临床试验进行综述。还获取了这些研究中与该主题相关的任何参考文献。
结果/结论：在已排除其他更常见咳嗽病因的咳嗽患者中，不完全或不可逆的气流受限、高分辨率CT扫描显示的小气道疾病或支气管镜检查发现的脓性分泌物，应提示非支气管扩张性化脓性气道疾病（细支气管炎）为潜在的主要病因。成功的管理取决于识别具体的潜在疾病。
