Machado Vitor Hugo Soares, Gregori Júnior Francisco
Universidade Estadual de Londrina, Hospital Evangélico de Londrina, Londrina, PR.
Arq Bras Cardiol. 2005 Dec;85(6):403-11. doi: 10.1590/s0066-782x2005001900006. Epub 2006 Jan 16.
Assess late cardiological evolution of children with rheumatic mitral regurgitation (RMR) who underwent mitral valve reconstructive surgery with implantation of Gregori's ring (MVR), from 1987 to 2003.
A study was conducted to analyze a series of cases of 43 children with RMR who underwent MVR with ages ranged from five to twelve years (mean age 9.7 +/- 2.2 years); 25 of the patients were females (58.1%). Patients were evaluated as per the following clinical parameters: functional class of heart failure, heart auscultation, electrocardiogram, chest X-ray and echocardiographic findings.
Forty-three patients underwent preoperative evaluation during the postoperative period, the number of patients evaluated decreased to 31 due to the fact that 6 patients had died and 6 others underwent valve replacement surgery. Follow-up was carried out for 100% of the patients. A significant reduction of heart failure functional class was observed. Mitral systolic murmur became less intense during the postoperative period. The cardiac area on chest X-ray and the presence of left ventricular overload on electrocardiogram were reduced, as well as the mitral regurgitation level on echocardiographic study. After 188 months, the survival rate was 82%, and the annual mortality rate, 0.38%. Thirty-one (72.6%) patients did not require reoperation and the annual rate of patients who required further surgery was 0.51%.
MVR is an effective procedure for treating RMR in children, resulting in a significant improvement of functional class, mitral systolic murmur and level of mitral regurgitation, as shown on Doppler echocardiogram.
评估1987年至2003年期间接受植入格雷戈里环二尖瓣重建手术(MVR)的风湿性二尖瓣反流(RMR)患儿的晚期心脏演变情况。
开展一项研究,分析43例年龄在5至12岁(平均年龄9.7±2.2岁)之间接受MVR的RMR患儿病例系列;其中25例患者为女性(58.1%)。根据以下临床参数对患者进行评估:心力衰竭功能分级、心脏听诊、心电图、胸部X线和超声心动图检查结果。
43例患者在术后接受了术前评估,由于6例患者死亡,另外6例接受了瓣膜置换手术,接受评估的患者数量降至31例。对所有患者进行了随访。观察到心力衰竭功能分级显著降低。二尖瓣收缩期杂音在术后期间强度减弱。胸部X线检查的心脏面积以及心电图上左心室负荷过重的情况均有所减少,超声心动图研究中的二尖瓣反流程度也有所降低。188个月后,生存率为82%,年死亡率为0.38%。31例(72.6%)患者无需再次手术,需要进一步手术的患者年发生率为0.51%。
MVR是治疗儿童RMR的有效方法,可使功能分级、二尖瓣收缩期杂音和二尖瓣反流程度在多普勒超声心动图上显示出显著改善。