Chetter I C, Mylankal K J, Hughes H, Fitridge R
Academic Vascular Surgical Unit, Vascular Laboratory, Hull Royal Infirmary, Alderson House, Anlaby Road, Hull HU3 2JZ, UK.
Br J Surg. 2006 Feb;93(2):169-74. doi: 10.1002/bjs.5261.
The aim was to compare early postoperative subjective outcome measures in a randomized trial of multiple stab incision phlebectomy (MSIP) and transilluminated powered phlebectomy (TIPP) for the treatment of varicose veins.
Patients having surgery for varicose veins were randomized to receive either MSIP or TIPP for local avulsion of varicose veins. Operating time, number of incisions and postoperative outcome were analysed in both groups. Quality of life (QoL) was analysed before and 1 and 6 weeks after surgery using domain-specific (Burford pain scale), disease-specific (Aberdeen Varicose Vein Questionnaire) and generic (Short Form 36 and EuroQol 5D) instruments.
Sixty-six patients consented to participate in the trial but four withdrew before surgery, so 33 patients underwent MSIP and 29 patients had TIPP. All patients had symptomatic or complicated varicose veins. There was no significant difference between groups in the total duration of surgery or the time taken for the avulsions. The number of incisions was significantly lower with TIPP. However, skin bruising at 1 and 6 weeks, and Burford pain score at 6 weeks were significantly higher in the TIPP group (P < 0.01 for bruising and P = 0.019 for pain). TIPP also had a greater adverse impact on generic QoL, resulting in a more prolonged recovery.
TIPP had the advantage of fewer surgical incisions, but was associated with more extensive bruising, prolonged pain and reduced early postoperative QoL.
本研究旨在比较多切口点状剥脱术(MSIP)和透光动力静脉切除术(TIPP)治疗静脉曲张的随机试验中术后早期的主观预后指标。
因静脉曲张接受手术的患者被随机分为接受MSIP或TIPP进行局部静脉曲张剥脱术两组。分析两组的手术时间、切口数量和术后结果。使用特定领域(伯福德疼痛量表)、疾病特异性(阿伯丁静脉曲张问卷)和通用(简明健康状况调查量表和欧洲五维健康量表)工具,在手术前、术后1周和6周分析生活质量(QoL)。
66例患者同意参与试验,但4例在手术前退出,因此33例患者接受了MSIP,29例患者接受了TIPP。所有患者均有症状性或复杂性静脉曲张。两组在手术总时长或剥脱所需时间方面无显著差异。TIPP的切口数量显著更少。然而,TIPP组在术后1周和6周时的皮肤瘀斑以及术后6周时的伯福德疼痛评分显著更高(瘀斑P < 0.01,疼痛P = 0.019)。TIPP对通用生活质量也有更大的不良影响,导致恢复时间更长。
TIPP具有手术切口更少的优势,但与更广泛的瘀斑、更长时间的疼痛以及术后早期生活质量降低有关。