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获得性无巨核细胞性血小板减少性紫癜

Acquired amegakaryocytic thrombocytopenic purpura.

作者信息

Agarwal Neeraj, Spahr Joseph E, Werner Theresa L, Newton David L, Rodgers George M

机构信息

Division of Hematology, Department of Internal Medicine, University of Utah Health Sciences Center, Salt Lake City, Utah 84132, USA.

出版信息

Am J Hematol. 2006 Feb;81(2):132-5. doi: 10.1002/ajh.20510.

Abstract

Acquired amegakaryocytic thrombocytopenia is an unusual hematologic disorder characterized by thrombocytopenia in association with markedly diminished bone marrow megakaryocytes. We report a case that responded to treatment with cyclosporine but not to IL-11. The bone marrow biopsy, repeated after resolution of thrombocytopenia, showed normal number of megakaryocytes.

摘要

获得性无巨核细胞性血小板减少症是一种罕见的血液系统疾病,其特征为血小板减少并伴有骨髓巨核细胞明显减少。我们报告一例对环孢素治疗有反应但对IL-11治疗无反应的病例。血小板减少症缓解后重复进行的骨髓活检显示巨核细胞数量正常。

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