Kutzenberger J, Pannek J, Stöhrer M
Klinik für Neuro-Urologie, Werner-Wicker-Klinik, Bad Wildungen.
Urologe A. 2006 Feb;45(2):158-60, 162-6. doi: 10.1007/s00120-005-0993-3.
There is no part of urology that has made so much progress in the last 25 years as neurourology. Seminal developments have been made in the selective effectiveness of drugs influencing neurogenic bladder dysfunction but having limited side effects. Additional advances are also likely to be made in the methods of functional electrostimulation and tissue engineering. Neurourology is predominantly influenced by our dynamic-functional understanding and the functionally oriented planning and implementation of treatment. The initial treatment options in many areas of neurourology are conservative, but, when possible, not irreversible. If these are ineffective or lead to late complications (e.g. by congenital paraplegia), there are a series of organ sparing or organ manipulating operations which can restore organ function. These make it possible to save kidney function from continuing damage, and, in many cases, to restore continence. The permanent indwelling catheter should remain excluded from the treatment of neurogenic bladder dysfunction. With adequate treatment, patients with neurogenic bladder dysfunction can be protected from severe complications and reintegrated into their normal social environment. After the acute phase of rehabilitation, urology is the most commonly required specialist area for paraplegic patients. In the past, urological problems have contributed most to the short lifespan of patients with an accident related spinal cord injury. Using modern neurourological treatment strategies, not only is lifespan increased but the quality of life of the patient is permanently improved.
在过去25年里,泌尿外科领域没有哪个分支像神经泌尿学那样取得了如此大的进展。在影响神经源性膀胱功能障碍的药物的选择性疗效方面取得了重大进展,且副作用有限。功能电刺激和组织工程方法也可能会有进一步进展。神经泌尿学主要受我们对动态功能的理解以及以功能为导向的治疗规划和实施的影响。神经泌尿学许多领域的初始治疗选择是保守的,但在可能的情况下并非不可逆转。如果这些方法无效或导致晚期并发症(如先天性截瘫),则有一系列保留器官或操作器官的手术可以恢复器官功能。这些手术能够避免肾功能持续受损,而且在许多情况下还能恢复控尿功能。神经源性膀胱功能障碍的治疗不应包括长期留置导尿管。通过适当治疗,神经源性膀胱功能障碍患者可以避免严重并发症,并重新融入正常社会环境。在康复急性期过后,泌尿外科是截瘫患者最常需要的专科领域。过去,泌尿系统问题是导致因意外脊髓损伤患者寿命缩短的最主要因素。采用现代神经泌尿学治疗策略,不仅能延长患者寿命,还能永久性提高患者生活质量。