Foy Karlissa, Bradley-Springer Lucy, Kempner Toni, Stevens Lyn, Gahagan LuAnn
Community Research Initiative of New England, Boston, MA, USA.
J Assoc Nurses AIDS Care. 2005 Mar-Apr;16(2):2-12. doi: 10.1016/j.jana.2005.01.004.
Enfuvirtide is the first of a new class of antiretrovirals know as fusion inhibitors approved for the treatment of HIV infection. It is administered via a subcutaneous injection. The patient is responsible for reconstitution from a powder and self-injection. Nurses caring for patients using enfuvirtide need a solid knowledge base about enfuvirtide administration and side effects in order to effectively educate and manage patients taking enfuvirtide. Enfuvirtide's safety and efficacy reported from phase III trials are summarized. Nursing guidelines were developed by the Association of Nurses in AIDS Care Expert Panel on Enfuvirtide. The guidelines, including suggestions on assessment, education, and management of side effects are reviewed. Teaching tools and resources are offered to assist in patient management. In addition, suggestions for proper syringe disposal and traveling with enfuvirtide are offered.
恩夫韦肽是一类被称为融合抑制剂的新型抗逆转录病毒药物中首个被批准用于治疗HIV感染的药物。它通过皮下注射给药。患者负责将粉末重新配置并自行注射。护理使用恩夫韦肽的患者的护士需要具备有关恩夫韦肽给药和副作用的扎实知识基础，以便有效地教育和管理服用恩夫韦肽的患者。总结了III期试验报告的恩夫韦肽的安全性和有效性。艾滋病护理护士协会恩夫韦肽专家小组制定了护理指南。对这些指南进行了审查，包括有关副作用评估、教育和管理的建议。提供了教学工具和资源以协助患者管理。此外，还提供了正确处理注射器以及携带恩夫韦肽旅行的建议。
