Carter James F, Sleeman Richard, Hill Jenny C, Idoine Fay, Titterton Emma L
Mass Spec Analytical Ltd., Building 20F, Golf Course Lane, P.O. Box 77, Filton, Bristol, BS99 7AR, UK.
Sci Justice. 2005 Jul-Sep;45(3):141-9. doi: 10.1016/S1355-0306(05)71648-8.
The versatility of isotope ratio mass spectrometry is demonstrated by reference to diverse case studies. Variations in the natural isotopic composition of non-biological, organic materials are compared as a means by which samples may be associated or discriminated. These techniques may be used to augment or compliment conventional forensic methodologies. delta13C analysis was used to demonstrate that different masking tape had been recovered in two, apparently similar cases, involving the smuggling of money. Visually similar ecstasy tablets were compared by consideration of the delta13C and delta15N composition of MDMA extracted from the tablets. Although only a limited number of tablets were analysed, the isotopic similarity between two different seizures was sufficient to induce a guilty plea from a person suspected of possessing both. A combination of delta2H, delta13C, delta15N and delta18O together with GC-MS analyses were applied to small samples of seized heroin. Although GC-MS analysis indicated differences between the chemical composition of two of the heroin samples, isotopic analysis suggested similarities, which were confirmed by further delta2H, delta13C and delta18O isotopic analysis of the clingfilm in which the samples were wrapped.
通过参考不同的案例研究证明了同位素比率质谱法的多功能性。比较了非生物有机材料天然同位素组成的变化，以此作为关联或区分样品的一种方法。这些技术可用于增强或补充传统的法医方法。δ13C分析被用于证明在两起看似相似的涉及货币走私的案件中查获了不同的胶带。通过考虑从摇头丸片剂中提取的MDMA的δ13C和δ15N组成，对外观相似的摇头丸片剂进行了比较。尽管仅分析了有限数量的片剂，但两次不同缉获物之间的同位素相似性足以使一名涉嫌持有两者的人认罪。将δ2H、δ13C、δ15N和δ18O与气相色谱-质谱分析相结合，应用于查获海洛因的小样本。尽管气相色谱-质谱分析表明两个海洛因样本的化学成分存在差异，但同位素分析显示出相似性，对包裹样本的保鲜膜进行进一步的δ2H、δ13C和δ18O同位素分析证实了这一点。
