Gupta M, Lyon F, Singh A D, Rundle P A, Rennie I G
Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, UK.
Eye (Lond). 2007 Apr;21(4):476-9. doi: 10.1038/sj.eye.6702227. Epub 2006 Jan 27.
To evaluate bovine pericardium (Tutopatch) as a wrapping material for hydroxyapatite implants in patients undergoing enucleation for uveal melanoma.
Prospective cohort study of patients who had enucleation for uveal melanoma between January 2003 and August 2003 were included in the study. Any patient with less than 3 months follow-up was excluded. Enucleation was performed under general anaesthesia followed by insertion of hydroxyapatite implants wrapped in bovine pericardium (Tutopatch). The recti muscles were sutured directly to the wrap. The tenon's capsule and conjunctiva were closed in two layers. A conformer was inserted at 1 week and artificial eye at 2-3 months. The patients were followed up regularly and were assessed for cosmetic result, exposure of implant, and the need for any further surgical procedures.
A total of 19 patients (seven male and 12 female) were included in the study. Median age at diagnosis was 63 years (range 38-80 years). Median follow-up was 26 months (range 22-30 months). No patient developed postoperative complications of wound dehiscence. The overall cosmetic result was excellent in all the patients. The rate of postoperative complications compared favourably with published data using other wrapping materials/implants.
Tutopatch is a safe wrapping material for hydroxyapatite orbital implants in patients undergoing enucleation for uveal melanoma.
评估牛心包(Tutopatch)作为葡萄膜黑色素瘤眼球摘除术患者羟基磷灰石植入物的包裹材料的效果。
对2003年1月至2003年8月因葡萄膜黑色素瘤接受眼球摘除术的患者进行前瞻性队列研究。排除随访时间少于3个月的患者。在全身麻醉下进行眼球摘除术,随后植入包裹在牛心包(Tutopatch)中的羟基磷灰石植入物。直肌直接缝合到包裹物上。Tenon囊和结膜分两层关闭。术后1周插入结膜囊填充物,2 - 3个月后安装义眼。定期对患者进行随访,评估美容效果、植入物暴露情况以及是否需要进一步的手术操作。
本研究共纳入19例患者(7例男性,12例女性)。诊断时的中位年龄为63岁(范围38 - 80岁)。中位随访时间为26个月(范围22 - 30个月)。没有患者出现伤口裂开的术后并发症。所有患者的整体美容效果均极佳。术后并发症发生率与使用其他包裹材料/植入物的已发表数据相比更具优势。
对于因葡萄膜黑色素瘤接受眼球摘除术的患者,Tutopatch是一种用于羟基磷灰石眼眶植入物的安全包裹材料。