Ma S Z, Li X H, Hu J
Department of Surgery, Beijing Chaoyang Hospital, Capital Medical University, 100020, Beijing, China.
Hernia. 2006 Jun;10(3):229-31. doi: 10.1007/s10029-006-0071-9. Epub 2006 Jan 27.
To investigate the clinical safety and effectiveness of acellular extracellular matrix (AEM) for inguinal hernia repair, 53 well-conducted and well-chosen sequential cases with inguinal hernia (56 inguinal hernias) were included in our multi-center study. All the inguinal hernias were repaired using conventional tension-free surgical procedures after being classified with Gilbert methods. No rejection was observed after operation. All the incisions healed well and no recurrence was found at the sixth month follow-up. At the seventh month after operation, one case of recurrence of right-side bilateral inguinal hernia (type IV) and another case of recurrence of left-side inguinal hernia (type V) were found. No other recurrence was observed at the 18th month follow-up. The AEM material has good histocompatibility and biomechanics characters and can be used for inguinal hernia repair. We observed no infection, chronic pain, funiculotesticular reaction, local nodular or feeling of discomfort after operation. But a further study of the usage of AEM in the repair of type IV and V inguinal hernias is still needed.
为研究脱细胞细胞外基质（AEM）用于腹股沟疝修补术的临床安全性和有效性，我们的多中心研究纳入了53例精心选择且实施良好的连续性腹股沟疝病例（共56侧腹股沟疝）。所有腹股沟疝采用吉尔伯特（Gilbert）方法分类后，均采用传统无张力手术进行修补。术后未观察到排斥反应。所有切口愈合良好，在术后6个月随访时未发现复发。术后7个月时，发现1例右侧双侧腹股沟疝（IV型）复发，另1例左侧腹股沟疝（V型）复发。在术后18个月随访时未观察到其他复发情况。AEM材料具有良好的组织相容性和生物力学特性，可用于腹股沟疝修补。我们观察到术后无感染、慢性疼痛、精索睾丸反应、局部结节或不适感觉。但仍需要进一步研究AEM在IV型和V型腹股沟疝修补中的应用。
