Noshita Nobuo, Kumabe Toshihiro, Kayama Takamasa, Tominaga Teiji
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Miyagi, Japan.
No Shinkei Geka. 2006 Jan;34(1):73-81.
The management of seven patients with choroid plexus tumors, 4 adults and 3 children (mean age 17.5 years) at our institution was reviewed. There were 4 cases of papilloma and 3 of carcinoma located in the lateral ventricle in 1 case, the third ventricle in 1 case, and the fourth ventricle in 5 cases. Total surgical excision was attempted in all patients. Total resection was achieved in three patients, resulting in no deficit in two and persistence of preoperative dysphagia in one. There was no recurrence after total resection. Subtotal resection was achieved in four patients, one of whom underwent second surgery resulting in total resection, and one patient died of respiratory disturbance after the third operation because of regrowth of the tumor. Complete excision could not be achieved in 3 of the 5 tumors located in the fourth ventricle because of extension to the brainstem. The median survival was 59.5 months for patients with papilloma, and 67.7 months for those with carcinoma. Adjuvant therapy was also required for carcinoma, one patient was treated by radiotherapy, and two by radiotherapy plus chemotherapy. Only one patient with papilloma was treated by radiotherapy plus chemotherapy postoperatively.
我们回顾了本机构收治的7例脉络丛肿瘤患者的治疗情况，其中4例为成人，3例为儿童（平均年龄17.5岁）。有4例乳头状瘤和3例癌，肿瘤位于侧脑室1例、第三脑室1例、第四脑室5例。所有患者均尝试进行手术全切。3例患者实现了全切，其中2例无功能缺损，1例术后仍存在术前吞咽困难。全切后无复发。4例患者实现了次全切，其中1例接受了二次手术实现了全切，1例患者在第三次手术后因肿瘤复发死于呼吸衰竭。位于第四脑室的5个肿瘤中有3个因侵犯脑干而无法实现完全切除。乳头状瘤患者的中位生存期为59.5个月，癌患者为67.7个月。癌患者还需要辅助治疗，1例患者接受了放疗，2例接受了放疗加化疗。只有1例乳头状瘤患者术后接受了放疗加化疗。
