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未接受手术治疗以及接受他汀类药物治疗与未接受他汀类药物治疗的患者长期随访中腹主动脉瘤的死亡率和大小

Mortality and size of abdominal aortic aneurysm at long-term follow-up of patients not treated surgically and treated with and without statins.

作者信息

Sukhija Rishi, Aronow Wilbert S, Sandhu Rasham, Kakar Pryanka, Babu Sateesh

机构信息

Cardiology Division, Department of Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York, USA.

出版信息

Am J Cardiol. 2006 Jan 15;97(2):279-80. doi: 10.1016/j.amjcard.2005.08.033. Epub 2005 Nov 21.

DOI:10.1016/j.amjcard.2005.08.033
PMID:16442379
Abstract

Of 130 patients with abdominal aortic aneurysms (AAAs) not treated surgically, 75 (58%) were treated with statins. The sizes of the AAAs were 4.6 +/- 0.6 cm at baseline and 4.5 +/- 0.6 cm at 23-month follow-up in patients treated with statins (p = NS) and 4.5 +/- 0.6 cm at baseline and 5.3 +/- 0.6 cm at 24-month follow-up in patients not treated with statins (p < 0.001). Four of 75 patients (5%) treated with statins died at 45-month follow-up, and 9 of 55 patients (16%) not treated with statins died at 44-month follow-up (p < 0.05).

摘要

在130例未接受手术治疗的腹主动脉瘤（AAA）患者中，75例（58%）接受了他汀类药物治疗。接受他汀类药物治疗的患者，腹主动脉瘤基线尺寸为4.6±0.6厘米，23个月随访时为4.5±0.6厘米（p=无统计学意义）；未接受他汀类药物治疗的患者，基线尺寸为4.5±0.6厘米，24个月随访时为5.3±0.6厘米（p<0.001）。接受他汀类药物治疗的75例患者中有4例（5%）在45个月随访时死亡，未接受他汀类药物治疗的55例患者中有9例（16%）在44个月随访时死亡（p<0.05）。

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