Pinakini K S, Kumar T S Mohan
Pharmacology, Melaka Manipal Medical College, Manipal 576104, India.
J Clin Forensic Med. 2006 Jul;13(5):274-6. doi: 10.1016/j.jcfm.2005.11.005. Epub 2006 Jan 27.
Poisoning is one of the most important causes of morbidity and mortality in developing countries like India. Anticholinesterase compounds like organophosphates (OP) and carbamates account for the majority of these poisoning cases because of their easy availability and agricultural use. Carbamates are as popular as OPs as insecticides that often go undiagnosed. A fatal case of carbofuran poisoning is presented where serial cholinesterase estimation played a major role in the diagnosis of the same. The pertinent medical literature on carbofuran poisoning is reviewed. The establishment of poison information center in each state is needed for proper diagnosis and management of poisoning cases.
在印度这样的发展中国家,中毒是发病和死亡的最重要原因之一。有机磷(OP)和氨基甲酸酯等抗胆碱酯酶化合物占这些中毒病例的大多数,因为它们易于获取且用于农业。氨基甲酸酯作为杀虫剂与有机磷一样常见,中毒情况常常未被诊断出来。本文介绍了一例呋喃丹中毒致死病例,其中连续胆碱酯酶测定在该病的诊断中起了主要作用。同时对有关呋喃丹中毒的相关医学文献进行了综述。为了对中毒病例进行正确诊断和管理,每个州都需要建立毒物信息中心。