Forrester Larry W, Hanley Daniel F, Macko Richard F
Baltimore Veterans Affairs Medical Center Rehabilitation Research Service, Baltimore, MD 21201, USA.
Arch Phys Med Rehabil. 2006 Feb;87(2):229-34. doi: 10.1016/j.apmr.2005.10.016.
To determine characteristics of transcranial magnetic stimulation (TMS)-induced measures of central motor excitability to the paretic and nonparetic quadriceps muscles of chronic hemiparetic stroke patients in the context of a short-term, submaximal bout treadmill exercise.
Cross-sectional.
Motor control and gait biomechanics laboratory.
Convenience sample of 11 patients including cohorts of treadmill untrained (n=8) and trained (n=3) stroke patients with chronic hemiparetic gait.
Short-term submaximal treadmill exercise.
Thresholds, amplitudes and latencies of TMS-induced motor evoked potentials at vastus medialis in paretic and nonparetic lower extremities.
Baseline characteristics of the motor evoked potentials (MEPs) show significantly higher motor thresholds, longer latencies, and reduced amplitudes on the paretic side. In cross-sectional comparisons a group of treadmill-trained patients had greater paretic MEP amplitude changes after treadmill exercise versus paretic MEP responses from a group of untrained patients.
These results indicate that treadmill training for 3 months or more may alter responsiveness of the lower-extremity central motor pathways to a short-term treadmill stimulus.
确定在短期、次最大强度的跑步机运动背景下，经颅磁刺激（TMS）对慢性偏瘫性卒中患者患侧和健侧股四头肌中央运动兴奋性的测量特征。
横断面研究。
运动控制与步态生物力学实验室。
11名患者的便利样本，包括未经跑步机训练（n = 8）和经过训练（n = 3）的慢性偏瘫步态卒中患者队列。
短期次最大强度跑步机运动。
患侧和健侧下肢股内侧肌TMS诱发运动诱发电位的阈值、波幅和潜伏期。
运动诱发电位（MEP）的基线特征显示，患侧运动阈值显著更高、潜伏期更长且波幅降低。在横断面比较中，一组经过跑步机训练的患者在跑步机运动后，患侧MEP波幅变化大于一组未经训练患者的患侧MEP反应。
这些结果表明，3个月或更长时间的跑步机训练可能会改变下肢中央运动通路对短期跑步机刺激的反应性。
