Berishvili K L, Rummo O O, Kirkovskiĭ V V, Tret'iak S I, Korotkov S V
Georgian Med News. 2005 Dec(129):7-11.
The aim of our investigation was to define the presence of correlation between toxicity of intestinal contents and clinical and laboratory indices in the cases of ileus and peritonitis with the use of complex method of enteral therapy. Experiments have been carried out on internodal cells of Nitella Flexilis water plant. Efficiency of the given method (investigation of toxicity of the intestinal content with the use of test-object Nitella Flexilis) has been studied in 25 patients, who underwent correction of morpho-functional status of small intestine. Results of investigation have shown that changes in toxicity of intestinal content reliably reflect the nature and dynamics of the pathobiologic processes proceeding in GIS in treated patients suffering from acute intestinal impassability. Using the method of correction of morpho-functional status of small intestine decreases the role of "Intestinal factor" in formation of endogenous intoxication, which in turn results in early normalization of clinical and laboratory indices, favored process of early post-operational period, decreased rate of lethality and shortened rehabilitation period.
我们研究的目的是通过使用复杂的肠内治疗方法，确定肠梗阻和腹膜炎病例中肠内容物毒性与临床及实验室指标之间的相关性。实验是在水蕴草的节间细胞上进行的。已对25例接受小肠形态功能状态纠正的患者研究了该方法（使用试验对象水蕴草研究肠内容物毒性）的有效性。研究结果表明，肠内容物毒性的变化可靠地反映了急性肠梗阻患者在接受治疗时胃肠道中发生的病理生物学过程的性质和动态。采用小肠形态功能状态纠正方法可降低“肠道因素”在内源性中毒形成中的作用，进而使临床和实验室指标早期恢复正常，有利于术后早期恢复过程，降低死亡率并缩短康复期。
