Gogiia T E, Kintraia N P
Georgian Med News. 2005 Dec(129):30-3.
We have done retrospective analysis of pregnancy, labor, delivery and neonatal period in 155 women with preterm labor. 78 of them delivered infants with intrauterine growth retardation (IUGR) and 77 women delivered immature infants compared to gestational age. Morphological changes are most prominent in fetal part of placenta, which disturbs blood flow to mother-fetus-placental unit, which in turn leads to intrauterine growth retardation and poor neonatal outcome -- in 78% of cases hypoxic-ischemic CNS disease, in 53% of cases occurs respiratory distress syndrome, pathological functional state and immature cerebral structures according to EEG. Based on case-control study it was documented, that preterm birth is one of the risk factors of IUGR, Odds Ratio is equal to 1.22. Preterm birth of any origin occurs in association with placental insufficiency.
我们对155例早产孕妇的妊娠、分娩及产褥期进行了回顾性分析。其中78例分娩出宫内生长受限（IUGR）的婴儿，77例分娩出与孕周不符的未成熟儿。胎盘胎儿部分的形态学改变最为显著，这会干扰母-胎-胎盘单位的血流，进而导致宫内生长受限和不良的新生儿结局——78%的病例出现缺氧缺血性中枢神经系统疾病，53%的病例发生呼吸窘迫综合征，根据脑电图显示存在病理功能状态和未成熟的脑结构。基于病例对照研究表明，早产是宫内生长受限的危险因素之一，优势比等于1.22。任何原因引起的早产都与胎盘功能不全有关。
