Akçam Timur, Karakoç Omer, Karahatay Serdar, Yetişer Sertaç
Department of Otolaryngology, Gülhane Military Medical School, Ankara, Turkey.
Kulak Burun Bogaz Ihtis Derg. 2005;15(5-6):97-102.
We evaluated the effect of external nasal dilator strips and local decongestants used either alone or in combination on the nasal airway.
The study included 23 volunteer males (mean age 24.3 years; range 21 to 36 years) with no complaints of nasal obstruction. Nasal airway dimensions were measured by acoustic rhinometry after the following applications: (i) no application; (ii) a placebo strip; (iii) a nasal dilator; (iv) a local decongestant; (v) a local decongestant followed by a placebo strip; and (vi) a local decongestant followed by a nasal dilator. Cross sectional areas (CSA1, CSA2, and CSA3) and three equal volumes (V1, V2, and V3) of the first 6 cm of the nasal airway were measured and compared with baseline values.
After applying nasal dilator strips, CSA1 and CSA2 significantly increased by 33% and 10%, respectively, with a significant increase in V1, whereas increases in V2 and V3 did not reach significance. The use of local decongestants was associated with significant increases in CSA1, CSA2, and CSA3 by 24%, 25%, and 18%, respectively, with a corresponding significant increase in V2 by 20%. Combined use of a local decongestant and nasal dilator resulted in significant increases in all areas and volumes compared with baseline values.
Combined use of external nasal dilators and local nasal decongestants produces a cumulative effect on cross sectional areas and nasal cavity volumes.
我们评估了外用鼻扩张条和局部减充血剂单独使用或联合使用对鼻气道的影响。
该研究纳入了23名无鼻塞主诉的男性志愿者（平均年龄24.3岁；范围21至36岁）。在以下操作后，通过鼻声反射测量鼻气道尺寸：（i）不进行操作；（ii）使用安慰剂条；（iii）使用鼻扩张器；（iv）使用局部减充血剂；（v）先使用局部减充血剂，再使用安慰剂条；（vi）先使用局部减充血剂，再使用鼻扩张器。测量鼻气道前6 cm的横截面积（CSA1、CSA2和CSA3）以及三个等体积（V1、V2和V3），并与基线值进行比较。
使用鼻扩张条后，CSA1和CSA2分别显著增加了33%和10%，V1显著增加，而V2和V3的增加未达到显著水平。使用局部减充血剂后，CSA1、CSA2和CSA3分别显著增加了24%、25%和18%，V2相应显著增加了20%。与基线值相比，局部减充血剂和鼻扩张器联合使用导致所有区域和体积均显著增加。
外用鼻扩张器和局部鼻减充血剂联合使用对横截面积和鼻腔容积产生累积效应。
