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N-乙酰-L-天门冬氨酸共振在卵巢黏液性囊腺瘤中的临床意义

Clinical significance of N-acetyl-L-aspartate resonance in ovarian mucinous cystadenoma.

作者信息

Hascalik S, Celik O, Sarac K, Alkan A, Mizrak B

机构信息

Department of Obstetrics and Gynecology, Medical Faculty, Turgut Ozal Medical Center, Inonu University, 44069 Malatya, Turkey.

出版信息

Int J Gynecol Cancer. 2006 Jan-Feb;16(1):423-6. doi: 10.1111/j.1525-1438.2006.00200.x.

DOI:10.1111/j.1525-1438.2006.00200.x
PMID:16445669
Abstract

Magnetic resonance spectroscopy (MRS) provides a noninvasive measurement of the biochemistry of living tissue. We report spectroscopy analysis of a 26-year-old woman affected by right ovarian lesion diagnosed as mucinous cystadenoma. MRS was performed by the point-resolved spectroscopy technique with a long echo time (TE) (136 msec). MRS measurements were performed on the two distinct component of the right ovarian tumor. The classification of metabolite peaks area in this study was performed according to the technique described by Okada et al. The features of proton MRS studies are discussed. As well as strongly elevated lactate and N-acetyl-L-aspartate signals, the tumor spectrum showed lipid resonances. Proton MRS imaging may be helpful for the investigation of the underlying pathophysiology of ovarian mucinous cystadenomas.

摘要

磁共振波谱(MRS)可对活体组织的生物化学进行无创测量。我们报告了对一名26岁患有右侧卵巢病变(诊断为黏液性囊腺瘤)女性的波谱分析。MRS采用具有长回波时间(TE)(136毫秒)的点分辨波谱技术进行。MRS测量针对右侧卵巢肿瘤的两个不同成分进行。本研究中代谢物峰面积的分类是根据冈田等人描述的技术进行的。讨论了质子MRS研究的特征。除了乳酸和N-乙酰-L-天冬氨酸信号强烈升高外,肿瘤波谱还显示出脂质共振。质子MRS成像可能有助于研究卵巢黏液性囊腺瘤的潜在病理生理学。

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