Takayama Osamu, Yokoyama Junkichi, Ito Shin
Department of Otolaryngology, Head and Neck Surgery, Tochigi Cancer Center, 4-9-13 Younan, Utunomiya, Tochigi 320-0834, Japan.
Auris Nasus Larynx. 2006 Jun;33(2):235-8. doi: 10.1016/j.anl.2005.11.006. Epub 2006 Jan 30.
Myoepithelial carcinoma is one of several new entities added to the updated classification of salivary gland tumors by the WHO in 1991. This tumor most frequently occurs in parotid gland. This is the first report presenting the tumor in floor of the mouth. It is a rare and prognostic poor cancer. Especially, there was not good therapy for recurrent cases. We treated the patient with repeated recurrences three times and presented in bilateral parapharyngeal space to skullbase in this time. We targeted function preservation and complete cure. In order to accomplish the both objections he received the superselective intra-arterial chemotherapy infused high-dose CDDP with radiation. We confirmed tumor free in FDG-PET in 2 months after the treatment. Now, we cannot detect any recurrence in 7 months after the treatment and he can eat anything and communicate anybody as before treated. We should follow-up him carefully.
肌上皮癌是世界卫生组织于1991年对唾液腺肿瘤进行更新分类时新增的几种肿瘤类型之一。这种肿瘤最常发生于腮腺。本文首次报道了发生于口腔底部的该肿瘤。它是一种罕见且预后较差的癌症。特别是，对于复发病例没有有效的治疗方法。我们治疗的这名患者已经复发三次，此次双侧咽旁间隙肿物已累及颅底。我们的目标是保留功能并实现根治。为了实现这两个目标，他接受了超选择性动脉内化疗，即注入高剂量顺铂并联合放疗。治疗后2个月，FDG-PET检查证实肿瘤消失。目前，治疗后7个月我们未发现任何复发迹象，他能够像治疗前一样正常饮食和与人交流。我们应密切随访他。
