Etienne T, Ruedin P, Goumaz C, Spiliopoulos A, Leski M, Mégevand R
Département de chirurgie, Hôpital cantonal universitaire, Genève.
Helv Chir Acta. 1992 May;58(6):899-904.
48 non primary renal transplants were performed in 40 recipients during the 1973-1990 period in our institution (40 second grafts, 6 third grafts and 1 four and fifth grafts). Despite poor HLA matching our second graft survival rates compare favorably with others (80% and 70%, 1 and 5 year graft survival rates). The type of immunosuppression (including ciclosporine A or not) and the duration of the first graft had an influence on the outcome of second grafts. Our experience with repeated retransplantation is limited, but graft survival appears to be poor: most of the grafts were rejected within 2 years (or less). However patient survival was not affected by overimmunosuppression following multiple grafts.
1973年至1990年期间，我们机构为40名受者进行了48例非原发性肾移植（40例第二次移植、6例第三次移植以及1例第四次和第五次移植）。尽管HLA配型不佳，但我们的第二次移植存活率与其他情况相比仍较为理想（1年和5年移植存活率分别为80%和70%）。免疫抑制类型（包括是否使用环孢素A）以及首次移植的持续时间对第二次移植的结果有影响。我们在反复再次移植方面的经验有限，但移植存活率似乎较低：大多数移植肾在2年（或更短时间）内被排斥。然而，多次移植后过度免疫抑制并未影响患者的存活率。
