Peavy G M, Rettenmaier M A, Berns M W
Beckman Laser Institute and Medical Clinic, College of Medicine, University of California-Irvine 92715.
J Am Vet Med Assoc. 1992 Jul 1;201(1):109-10.
The combined use of CO2 laser ablation and doxorubicin hydrochloride (30 mg/m2) administered twice, 4 weeks apart, resulted in complete remission of vaginal fibrosarcoma in a 10-year-old Miniature Poodle. The tumor had redeveloped when only CO2 ablation was used for treatment and doxorubicin hydrochloride alone has had marginal influence on fibrosarcomas; however, use of both treatments in this dog resulted in a 20-month, disease-free period. This treatment combination was minimally traumatic to the dog, easily accomplished, and effective, and it allowed retention of the normal anatomy and function of the urogenital tract.
对一只10岁的迷你贵宾犬，联合使用二氧化碳激光消融术和间隔4周给药两次的盐酸多柔比星（30毫克/平方米），使其阴道纤维肉瘤完全缓解。仅使用二氧化碳消融术治疗时肿瘤复发，单独使用盐酸多柔比星对纤维肉瘤的影响甚微；然而，对这只犬同时使用这两种治疗方法，使其获得了20个月的无病期。这种治疗组合对犬的创伤极小，操作简便且有效，还能保留泌尿生殖道的正常解剖结构和功能。
