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参加奥运会铁人三项赛的运动员体内的B型利钠肽

B-type natriuretic peptide in athletes performing an Olympic triathlon.

作者信息

Banfi G, Migliorini S, Dolci A, Noseda M, Scapellato L, Franzini C

机构信息

Istituto Ortopedico Galeazzi, Milan, Italy.

出版信息

J Sports Med Phys Fitness. 2005 Dec;45(4):529-31.

Abstract

AIM

Brain natriuretic peptide (BNP) is a cardioactive molecule produced in the myocardium. BNP is a sensitive marker of cardiac failure and its measurement in blood could be useful to the diagnosis and the treatment of this disease. Sporting activities, especially endurance ones, can induce cardiac problems, owing to the high workload for the myocardium during long and ultralong heavy effort. There are 2 papers describing the behavior of BNP in endurance events. BNP was elevated in marathoners, immediately after the race and also after 4 h. We studied the behavior of BNP in the triathlon, which is a complex sport characterized by 3 different activities (swimming, cycling, running).

METHODS

We recruited 49 athletes, all males, except for 4 females; 2 athletes did not finish the race and were not included in the statistical analysis in 2 different competitions. In these subjects we measured BNP using an immunological method before and after a triathlon.

RESULTS

No statistical significance between BNP values, before and after the triathlon, was found.

CONCLUSIONS

We found no significant differences between pre- and postcompetition BNP values. Moreover, the range of values in both the blood drawings are similar of those of the general population, representing the biological variability of the analyte. The values in regularly trained athletes,, are not different from the general population and BNP is not modified by a triathlon, a typical endurance sport performance. We can underline that BNP increases in plasma are induced by heavy pathologies and are not influenced by physical activities, even strenuous ones.

摘要

目的

脑钠肽(BNP)是一种在心肌中产生的具有心脏活性的分子。BNP是心力衰竭的敏感标志物,检测血液中的BNP对该疾病的诊断和治疗可能有用。体育活动,尤其是耐力运动,可能会引发心脏问题,这是由于在长时间和超长距离的高强度运动中,心肌承受的工作量很大。有两篇论文描述了BNP在耐力运动中的表现。马拉松运动员在比赛结束后即刻以及4小时后BNP水平升高。我们研究了BNP在铁人三项运动中的表现,铁人三项是一项复杂的运动,由三种不同的活动(游泳、骑自行车、跑步)组成。

方法

我们招募了49名运动员,除4名女性外均为男性;在两项不同的比赛中,有2名运动员未完成比赛,未纳入统计分析。在这些受试者中,我们在铁人三项比赛前后采用免疫学法测量BNP。

结果

铁人三项比赛前后的BNP值之间未发现统计学差异。

结论

我们发现比赛前后的BNP值无显著差异。此外,两次采血的BNP值范围与普通人群相似,体现了分析物的生物学变异性。经常训练的运动员的BNP值与普通人群无异,并且铁人三项这项典型的耐力运动表现不会改变BNP值。我们可以强调,血浆中BNP升高是由严重病变引起的,不受体育活动影响,即使是剧烈的体育活动也不会影响。

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