Aidar Renata Chade, Suzuki Fábio A
Instituto de Assistência Médica ao Servidor Estadual Francisco Morato de Oliveira, SP.
Braz J Otorhinolaryngol. 2005 Jan-Feb;71(1):48-54. doi: 10.1016/s1808-8694(15)31284-2. Epub 2006 Jan 2.
To evaluate vestibular evoked myogenic potentials in patients with multiple sclerosis as method of diagnostic support.
Case-control.
We studied a group of normal individuals (n=15) and a Studied group (n=15) that comprised patients with diagnosis of multiple sclerosis. Both groups were submitted to vestibular evoked myogenic potential exam. In each ear it was applied 200 stimuli by clicks and repeated for 2 consecutive cycles with the purpose of evaluating reproducibility. The active electrode of surface was put on the superior S++ of sternocleidomastoid muscle and the reference electrode on the anterior border of the clavicle. The individuals were instructed to rotate theirs head to the opposite side to the stimulated ear.
Vestibular evoked myogenic potential responses were prompt, reproducible and biphasic. The latency of wave P1 and N2 and P1-N2 amplitude showed a higher value in the studied group when compared with the normal group. There was no significant difference when the ears were compared in P1 and N2 amplitude. We noticed that individuals with multiple sclerosis showed no response in 30% of the cases. In evaluating the individuals of the Studied group with otoneurology symptoms and compared with individuals without symptoms, it was observed that P1 and N2 latencies and P1-N2 amplitude were higher in symptomatic cases.
Vestibular evoked myogenic potential was considered a good method of diagnostic support of vestibulospinal tract in cases of multiple sclerosis.
评估多发性硬化症患者的前庭诱发肌源性电位,作为一种诊断辅助方法。
病例对照研究。
我们研究了一组正常个体(n = 15)和一组研究对象(n = 15),研究对象为被诊断为多发性硬化症的患者。两组均接受前庭诱发肌源性电位检查。在每只耳朵施加200次点击刺激,并连续重复2个周期,以评估可重复性。表面活性电极置于胸锁乳突肌的上S++处,参考电极置于锁骨前缘。受试者被指示将头部转向受刺激耳朵的对侧。
前庭诱发肌源性电位反应迅速、可重复且为双相性。与正常组相比,研究组的P1波和N2波潜伏期以及P1 - N2波幅显示出更高的值。在比较耳朵的P1和N2波幅时,没有显著差异。我们注意到,30%的多发性硬化症患者没有反应。在评估有耳神经学症状的研究组个体并与无症状个体进行比较时,发现有症状病例的P1和N2潜伏期以及P1 - N2波幅更高。
在前庭脊髓束多发性硬化症病例中,前庭诱发肌源性电位被认为是一种良好的诊断辅助方法。