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[氧化亚氮全身麻醉患者鼓室导抗图改变的评估]

[Evaluation of tympanometric alterations in patients subject to general anesthesia with nitrous oxide].

作者信息

Teixeira Fernanda Mossumez Fernandes, Tomita Shiro, de Lima Marco Antônio de Melo Tavares

机构信息

Universidade Federal do Rio de Janeiro.

出版信息

Braz J Otorhinolaryngol. 2005 May-Jun;71(3):274-80. doi: 10.1016/s1808-8694(15)31323-9. Epub 2005 Dec 14.

Abstract

itrous oxide is an inhaling gas that can increase intratympanic pressure during the anesthetic act and cause negative pressure after it is discontinued, mainly in patients with Eustachian tube dysfunction. These pressure variations may come up with clinical implications such as tympanic membrane rupture, ossicular system disarticulation, haemotympanum, barotraumas, prosthesis displacement stapaedotomy and tympanic graft lateralization after tympanoplasty, in addition to serous fluid entrance into the middle ear during the negative pressure phase. : To evaluate the nitrous oxide influence on the middle ear pressure in a population without tube malfunction performing pre and postoperative tympanometry. : Transversal cohort. : A prospective study was carried out with Universitário Clementino Fraga Filho Hospital- UFRJ inpatients submitted to general anesthesia with the use of 50% nitrous oxide from April to June 2003. It was also evaluated whether the duration of surgery, associated anesthetics, presence of allergic rhinitis and nasal septal deviation could contribute to the onset of intratympanic pressure alteration. : The sample was made up of 50 patients and in almost half of them (48%), postoperative tympanometry alterations (type C curve) were found when comparing to preoperative tympanometric control (type A curve). Neither gender nor age interfered in the onset of postoperative tympanometry alterations, similarly to surgery duration. The associated volatile anesthetic type, nasal septal deviation and allergic rhinitis were not able to influence postoperative middle ear pressure. : Nitrous oxide modifies intratympanic pressure during the anesthetic act and after its discontinuation.

摘要

氧化亚氮是一种吸入性气体,在麻醉过程中可增加鼓室内压力,停止使用后会导致负压,主要发生在咽鼓管功能障碍的患者中。这些压力变化可能会产生临床影响,如鼓膜破裂、听骨链脱节、鼓室积血、气压伤、人工听骨移位、镫骨切除术以及鼓室成形术后鼓膜移植物侧移,此外在负压阶段还会有浆液进入中耳。目的:评估氧化亚氮对无咽鼓管功能障碍人群中耳压力的影响,在术前和术后进行鼓室导抗图测量。横向队列研究。2003年4月至6月,对里约热内卢联邦大学克莱门蒂诺·弗拉加·菲略大学医院的住院患者进行了一项前瞻性研究,这些患者接受了使用50%氧化亚氮的全身麻醉。还评估了手术时间、联合使用的麻醉剂、过敏性鼻炎和鼻中隔偏曲是否会导致鼓室内压力改变。样本由50名患者组成,与术前鼓室导抗图对照(A型曲线)相比,几乎一半(48%)的患者术后鼓室导抗图出现改变(C型曲线)。性别和年龄均未影响术后鼓室导抗图改变的发生,手术时间也是如此。联合使用的挥发性麻醉剂类型、鼻中隔偏曲和过敏性鼻炎均无法影响术后中耳压力。氧化亚氮在麻醉过程中及停止使用后会改变鼓室内压力。

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本文引用的文献

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Nitrous oxide: time to stop laughing?一氧化二氮:是时候停止“笑气”的使用了吗?
Anaesthesia. 1998 Mar;53(3):213-5. doi: 10.1046/j.1365-2044.1998.00412.x.
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Effect of anesthetic gas on middle ear fluid.麻醉气体对中耳积液的影响。
Laryngoscope. 1994 Jul;104(7):832-6. doi: 10.1288/00005537-199407000-00009.
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Spontaneous rupture of the tympanic membrane during anaesthesia.麻醉期间鼓膜自发性破裂。
J Laryngol Otol. 1994 Jul;108(7):582-3. doi: 10.1017/s0022215100127483.
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Direct demonstration of gas diffusion into the middle ear.气体扩散至中耳的直接证明。
Acta Otolaryngol. 1995 Mar;115(2):276-8. doi: 10.3109/00016489509139308.

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