Limares Fabrícia Dias Colombano, Soler Rita De Cássia, Bussoloti Filho Ivo
Faculdade de Ciências Médicas de São Paulo.
Braz J Otorhinolaryngol. 2005 May-Jun;71(3):342-5. doi: 10.1016/s1808-8694(15)31333-1. Epub 2005 Dec 14.
jögren's Syndrome (SS) is considered a multisystemic chronic disorder, which is characterized by a lymphocytic infiltration of exocrine glands and autoantibodies production. : Several studies have demonstrated increased incidence of Lymphoma in SS patients. Our study tries to determine this relation. : Transversal cohort. : Patients with Sicca's Syndrome from the Stomathology service, Santa Casa de Misericórdia Hospital, in Sao Paulo, ENT Department, from July 1999 to April 2002. : Out of 39 patients, 24 were diagnose as SS. Ages ranged from 19 to 83 years old, with predominance of women (69.7%). Time between the first symptoms and SS diagnosis were variable, ranging within 3.77 years. None of the analyzed patients developed lymphoma. : Both SS early diagnosis and the increased risk of lymphoma's development in those patients are important, reason why long-term follow-up is essential. We observed that our findings were different from those in the literature. We did not detect any cases of lymphoma in our patients.
干燥综合征(SS)被认为是一种多系统慢性疾病,其特征是外分泌腺淋巴细胞浸润和自身抗体产生。多项研究表明,SS患者淋巴瘤的发病率增加。我们的研究试图确定这种关系。横向队列研究。1999年7月至2002年4月,圣保罗圣卡塔琳娜慈善医院口腔科和耳鼻喉科的口干燥症患者。在39名患者中,24名被诊断为SS。年龄范围为19至83岁,女性占主导(69.7%)。首次出现症状至SS诊断的时间各不相同,在3.77年范围内。分析的患者中无一例发生淋巴瘤。SS的早期诊断以及这些患者发生淋巴瘤的风险增加都很重要,因此长期随访至关重要。我们观察到我们的研究结果与文献中的不同。我们的患者中未检测到任何淋巴瘤病例。