Liu Da-qing, Pei Xue-tao
Department of Stem Cell and Regenerative Medicine, Institute of Blood Transfusion, Academy of Military Medical Science, Beijing 100850, China.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2005 Dec;27(6):659-61.
Cancer stem cells are defined as rare cells in cancer tissues with indefinite potential for self-renewal that drives tumorigenesis. It was first extensively documented for leukaemia and multiple myeloma. It has also been found in solid cancers such as human breast cancer and nervous system tumors. Studies of cancer stem cell biology and mechanisms of tumorigenesis are lending insight into the origins of cancer and will ultimately yield new approaches to fight cancer.
癌症干细胞被定义为癌症组织中具有无限自我更新潜能的稀有细胞，这种潜能驱动肿瘤发生。它最早在白血病和多发性骨髓瘤中得到广泛记载。在实体癌中也已发现，如人类乳腺癌和神经系统肿瘤。对癌症干细胞生物学及肿瘤发生机制的研究正在深入了解癌症的起源，并最终将产生抗击癌症的新方法。
