Ricucci Domenico, Pascon Elizeu A, Ford Thomas R Pitt, Langeland Kaare
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006 Feb;101(2):239-49. doi: 10.1016/j.tripleo.2005.03.038. Epub 2005 Sep 26.
The purpose of this study was to evaluate 50 human periapical lesions for bacteria and epithelium in a case study in dental practice.
Specimens were obtained from the extraction of 50 untreated teeth that had lesions attached to their apices. The specimens were histologically evaluated using serial sections.
Bacteria were found in all teeth, colonizing necrotic tissue in the main canal, dentinal tubules, or apical ramifications, and in the body of the periapical lesion in 18 abscesses or cysts. Twenty-one lesions were epithelialized; 14 abscesses, 20 granulomas, and 16 cysts were distinguished. In 18 root canals inflamed tissue was found in the apical part of the canal. A single foramen was present in 13 cases while apical ramifications were found in 37 cases.
Granulomas were most common, and most epithelialized lesions were cysts. Bacteria were only detected periapically in abscesses or cysts. Inflamed tissue was present in the apical root canal in one third of cases.
本研究旨在通过一项牙科实践案例研究，评估50例人类根尖周病变中的细菌和上皮情况。
从50颗未经治疗且根尖有病变的牙齿拔除标本中获取样本。使用连续切片对标本进行组织学评估。
所有牙齿均发现细菌，细菌定殖于主根管、牙本质小管或根尖分支的坏死组织中，以及18例脓肿或囊肿的根尖周病变组织中。21个病变出现上皮化；区分出14例脓肿、20例肉芽肿和16例囊肿。18个根管的根尖部分发现有炎症组织。13例存在单一根尖孔，37例发现根尖分支。
肉芽肿最为常见，大多数上皮化病变为囊肿。仅在脓肿或囊肿的根尖周检测到细菌。三分之一的病例根尖根管存在炎症组织。
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