氟康唑和别嘌呤醇成功治疗一例肾衰竭患者的内脏利什曼病。
Successful treatment of visceral leishmaniasis with fluconazole and allopurinol in a patient with renal failure.
作者信息
Colakoglu Murat, Yaylali Guzin Fidan, Colakoglu Nagihan Yalcin, Yilmaz Mustafa
机构信息
Departments of Nephrology, School of Medicine, Pamukkale University, Denizli, Turkey.
出版信息
Scand J Infect Dis. 2006;38(2):152-4. doi: 10.1080/00365540500277201.
PMID:16449014
Abstract
Standard treatments for visceral leishmaniasis (antimonials, amphotericin B and pentamidine) pose several problems. Failure of antimonials or severe toxicity is particularly troublesome in patients with renal insufficiency. We report a case of visceral leishmaniasis and renal insufficiency successfully treated with fluconazole and allopurinol for 4 months.
摘要
内脏利什曼病的标准治疗方法（锑剂、两性霉素B和喷他脒）存在一些问题。对于肾功能不全的患者，锑剂治疗失败或出现严重毒性尤其棘手。我们报告了1例内脏利什曼病合并肾功能不全的患者，使用氟康唑和别嘌醇成功治疗4个月的病例。
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