Lekwauwa Ruby, McQuoid Douglas, Steffens David C
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina 27710, USA.
J Geriatr Psychiatry Neurol. 2006 Mar;19(1):21-5. doi: 10.1177/0891988705284724.
Predicting memory problems in older depressed patients receiving electroconvulsive therapy (ECT) is difficult. In this study, hippocampal volume and acute memory outcomes were examined in 15 patients following an index course of ECT. Smaller hippocampal volume was associated with poorer ECT-related memory outcomes. These results add to a growing literature on memory, ECT, and the hippocampus. Although the findings are significant, the sample size in the study is small, so future studies with more complex modeling of key variables that may influence memory are warranted.
预测接受电休克治疗（ECT）的老年抑郁症患者的记忆问题具有挑战性。在本研究中，对15例接受ECT治疗的患者在一个疗程后的海马体积和急性记忆结果进行了检查。较小的海马体积与ECT相关的较差记忆结果有关。这些结果进一步丰富了关于记忆、ECT和海马体的文献。尽管这些发现具有重要意义，但该研究的样本量较小，因此有必要开展未来研究，对可能影响记忆的关键变量进行更复杂的建模。
