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新千年青少年特发性脊柱侧弯脊柱融合术的并发症。脊柱侧弯研究学会发病率与死亡率委员会报告

Complications in spinal fusion for adolescent idiopathic scoliosis in the new millennium. A report of the Scoliosis Research Society Morbidity and Mortality Committee.

作者信息

Coe Jeffrey D, Arlet Vincent, Donaldson William, Berven Sigurd, Hanson Darrell S, Mudiyam Ram, Perra Joseph H, Shaffrey Christopher I

机构信息

Center for Spinal Deformity and Injury, Suite 1F, 360 Dardanelli Lane, Los Gatos, CA 95032, USA.

出版信息

Spine (Phila Pa 1976). 2006 Feb 1;31(3):345-9. doi: 10.1097/01.brs.0000197188.76369.13.

DOI:10.1097/01.brs.0000197188.76369.13
PMID:16449909
Abstract

STUDY DESIGN

The Morbidity and Mortality database of the Scoliosis Research Society (SRS) was queried as to the incidence and type of complications as reported by its members for the treatment of adolescent idiopathic scoliosis (AIS) with spinal fusion and instrumentation procedures regarding surgical approach (anterior, posterior, or combined anterior-posterior) during a recent 3-year period.

OBJECTIVE

To evaluate the incidence of surgeon-reported complications in a large series of spinal fusions with instrumentation for a single spinal deformity diagnosis and age group regarding surgical approach.

SUMMARY OF BACKGROUND DATA

The SRS has been collecting morbidity and mortality data from its members since its formation in 1965 with the intent of using these data to assess the complications and adverse outcomes (death and/or spinal cord injury) of surgical treatment for spinal deformity. Surgical approaches to the management of treatment of AIS have a measurable impact on efficacy of correction, levels fused, and operative morbidity. However, there is a lack of consensus on the choice of surgical approach for the treatment of spinal deformity.

METHODS

Of the 58,197 surgical cases submitted by members of the SRS in the years 2001, 2002, and 2003, 10.9% were identified as having had anterior, posterior, or combined spinal fusion with instrumentation for the diagnosis of AIS, and comprised the study cohort. All reported complications were tabulated and totaled for each of the 3 types of procedures, and statistical analysis was conducted.

RESULTS

Complications were reported in 5.7% of the 6334 patients in this series. Of the 1164 patients who underwent anterior fusion and instrumentation, 5.2% had complications, of the 4369 who underwent posterior instrumentation and fusion, 5.1% had complications, and of the 801 who underwent combined instrumentation and fusion, 10.2% had complications. There were 2 patients (0.03%) who died of their complications. There was no statistical difference in overall complication rates between anterior and posterior procedures. However, the difference in complication rates between anterior or posterior procedures compared to combined procedures was highly significant (P < 0.0001). The differences in neurologic complication rates between combined and anterior procedures, as well as combined and posterior procedures were also highly statistically significant (P < 0.0001), but not between anterior and posterior procedures.

CONCLUSIONS

This study shows that complication rates are similar for anterior versus posterior approaches to AIS deformity correction. Combined anterior and posterior instrumentation and fusion has double the complication rate of either anterior or posterior instrumentation and fusion alone. Combined anterior and posterior instrumentation and fusion also has a significantly higher rate of neurologic complications than anterior or posterior instrumentation and fusion alone.

摘要

研究设计

查询了脊柱侧弯研究学会(SRS)的发病率和死亡率数据库,以了解其成员报告的在最近3年期间采用脊柱融合及内固定手术治疗青少年特发性脊柱侧弯(AIS)时,根据手术入路(前路、后路或前后联合)出现的并发症的发生率及类型。

目的

评估在一大系列针对单一脊柱畸形诊断和年龄组采用内固定的脊柱融合手术中,根据手术入路,外科医生报告的并发症的发生率。

背景数据总结

自1965年成立以来,SRS一直在收集其成员的发病率和死亡率数据,目的是利用这些数据评估脊柱畸形手术治疗的并发症和不良后果(死亡和/或脊髓损伤)。AIS治疗的手术入路对矫正效果、融合节段和手术发病率有可测量的影响。然而,对于脊柱畸形治疗的手术入路选择缺乏共识。

方法

在SRS成员于2001年、2002年和2003年提交的58197例手术病例中,10.9%被确定为因AIS诊断而进行了前路、后路或前后联合脊柱融合及内固定手术,组成了研究队列。对所有报告的并发症进行列表统计,分别统计这3种手术类型的并发症总数,并进行统计分析。

结果

本系列6334例患者中有5.7%报告出现并发症。在1164例行前路融合及内固定的患者中,5.2%出现并发症;在4369例行后路内固定及融合的患者中,5.1%出现并发症;在801例行联合内固定及融合的患者中,10.2%出现并发症。有2例患者(0.03%)死于并发症。前路和后路手术的总体并发症发生率无统计学差异。然而,前路或后路手术与联合手术的并发症发生率差异非常显著(P<0.0001)。联合手术与前路手术以及联合手术与后路手术之间的神经并发症发生率差异也具有高度统计学意义(P<0.0001),但前路和后路手术之间无差异。

结论

本研究表明,AIS畸形矫正的前路和后路手术并发症发生率相似。前后联合内固定及融合的并发症发生率是单独前路或后路内固定及融合的两倍。前后联合内固定及融合的神经并发症发生率也明显高于单独的前路或后路内固定及融合。

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