Ansari Husam, Garibaldi Daniel C, Jun Albert S
Clin Exp Ophthalmol. 2006 Jan-Feb;34(1):81-3. doi: 10.1111/j.1442-9071.2006.01152.x.
Two patients, both with a history of major depressive disorder, presented with large bilateral corneal epithelial defects and ring-shaped stromal opacities. Both were initially treated unsuccessfully with topical antibiotic therapy for presumed infectious keratitis. One patient eventually admitted to topical anaesthetic abuse. In the second patient, signs of topical anaesthetic abuse and Munchausen's syndrome became evident. Cessation of anaesthetic use resulted in rapid resolution of the corneal epithelial defects in both patients. Anaesthetic abuse keratopathy is often a manifestation of underlying psychiatric illness, and psychiatric intervention is a very important part of management. To the authors' knowledge, this is the first report of ocular Munchausen's syndrome manifesting as anaesthetic abuse keratopathy.
两名均有重度抑郁症病史的患者出现双侧角膜上皮大面积缺损及环形基质混浊。两人最初均因疑似感染性角膜炎接受局部抗生素治疗，但未成功。其中一名患者最终承认滥用局部麻醉剂。在第二名患者中，滥用局部麻醉剂及孟乔森综合征的迹象变得明显。停止使用麻醉剂后，两名患者的角膜上皮缺损均迅速得到缓解。麻醉剂滥用性角膜病变通常是潜在精神疾病的一种表现，精神科干预是治疗的非常重要的一部分。据作者所知，这是首例表现为麻醉剂滥用性角膜病变的眼部孟乔森综合征报告。
