Achtari Chahin, Meyer Sylvain, De Grandi Pierre
Urogynaecology Department, Mercy Hospital for Women, East Melbourne, VIC, Australia.
Gynakol Geburtshilfliche Rundsch. 2006;46(1-2):39-44. doi: 10.1159/000089976.
Bulking agents are used in the treatment of urinary stress incontinence associated with intrinsic sphincter deficiency. Bovine collagen remains the gold standard despite problems such as allergic reaction and absorption of the injected material. Several new products are being evaluated or used clinically to try and overcome problems linked with bovine collagen. The aim of this paper is to review the bulking agents available and to put in prospect use of these products with the recent progress made in the treatment of urinary stress incontinence. The gold standard treatment for intrinsic sphincter deficiency is suburethral autologous or synthetic suburethral slings. Bulking agents are indicated for multi-operated patients with urinary stress incontinence and intrinsic sphincter deficiency. Bladder neck hypermobility is not a contraindication.
填充剂用于治疗与固有括约肌缺陷相关的压力性尿失禁。尽管存在诸如过敏反应和注射材料吸收等问题，牛胶原蛋白仍然是金标准。目前正在评估几种新产品或在临床上使用，以试图克服与牛胶原蛋白相关的问题。本文的目的是回顾现有的填充剂，并结合压力性尿失禁治疗的最新进展展望这些产品的应用。固有括约肌缺陷的金标准治疗方法是尿道下自体或合成尿道下吊带。填充剂适用于患有压力性尿失禁和固有括约肌缺陷的多次手术患者。膀胱颈活动过度不是禁忌证。
