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奥地利神经科学简史。

A short history of neurosciences in Austria.

作者信息

Jellinger K A

机构信息

Institute of Clinical Neurobiology, Vienna, Austria.

出版信息

J Neural Transm (Vienna). 2006 Mar;113(3):271-82. doi: 10.1007/s00702-005-0400-7.

Abstract

Based on internal medicine and psychiatry and in close connection with pathology, the neurosciences in Austria began to develop in the 18(th) century, e.g. with the description of inflammation of the central nervous system by J. P. Franck (1745-1823) and the "phrenology" by F. J. Gall (1745-1823). Under the influence of the great pathologist C. Rokitansky (1804-1878), the tripode of the Vienna neurology - L. Türck (1810-1868), as initiator, Th. v. Meynert (1833-1892) the activator, and H. Obersteiner (1847-1922) as the founder of the Vienna Neurological Institute, presented basic contributions to the morphology and pathology of the nervous system. At the end of the 19(th) and in the early 20(th) century, they were followed by important publications by S. Fred (aphasia), C. Redlich (tabes dorsalis), F. Sträussler (CNS syphilis), A. Spitzer (fiber anatomy of the brain), P. Schilder (diffuse sclerosis), R. Barany (Nobel price for physiology and medicine 1914), J. Wagner v. Jauregg (Nobel price for medicine, 1927), O. Loewi (Nobel Price for Physiology and Medicine together with Sir H. Dale, 1936), A. Schüller (histiocytosis X), C. v. Economo (encephalitis lethargica and cytoarchitectonics of the human cerebral cortex), E. Pollak (Wilson disease), E. Gamper (mesencephalic subject), J. Gerstmann (Gerstmann-Sträussler-Scheinker syndrome and Gerstmann parietal syndrome), H. Hoff with L. Schönbauer (brain tumors and surgery), and others. Major research institutions were the departments of psychiatry I and II at the University of Vienna School of Medicine (foundation 1870), unification 1911, separation into departments of neurology, psychiatry and neuropsychiatry of children and adolescents in 1971), the Obersteiner Institute in Vienna (foundation 1882, separation 1993), the university departments at Graz and Innsbruck, both founded in 1891, and other laboratories, where renouned clinicans and neuroscientists, like O. Marburg, H. Hoff, O. Pötzl, O. Kauders, F. Seitelberger, H. Tschabitscher, K. Weingarten, H. Reisner,W. Birkmayer, H. Petsche, F. Gerstenbrand, H. Bernheimer, H. W. Heiss, H. Lassmann, W. Poewe, L. Deecke, and many of their associates produced important contributions to wide areas of modern neurosciences. Important for the future are the foundation of the Institute of Brain Research at Vienna Medical University and of the Austrian Society of Neurology which will give further impact for the future progress of neuroscience research in Austria and its integration into the international science community.

摘要

基于内科医学和精神病学,并与病理学紧密相连,奥地利的神经科学于18世纪开始发展,例如J. P. 弗兰克(1745 - 1823)对中枢神经系统炎症的描述以及F. J. 加尔(1745 - 1823)的“颅相学”。在伟大的病理学家C. 罗基坦斯基(1804 - 1878)的影响下,维也纳神经学的三巨头——L. 图尔克(1810 - 1868,发起者)、Th. v. 迈纳特(1833 - 1892,推动者)以及H. 奥伯施泰纳(1847 - 1922,维也纳神经学研究所创始人),为神经系统的形态学和病理学做出了基础性贡献。在19世纪末和20世纪初,随后有S. 弗雷德(失语症)、C. 雷德利希(脊髓痨)、F. 施特劳斯勒(中枢神经系统梅毒)、A. 施皮策(脑纤维解剖学)、P. 希尔德(弥漫性硬化症)、R. 巴拉尼(1914年诺贝尔生理学和医学奖)、J. 瓦格纳·冯·尧雷格(1927年诺贝尔医学奖)、O. 勒维(与H. 戴尔爵士共同获得1936年诺贝尔生理学和医学奖)、A. 许勒(组织细胞增多症X)、C. v. 埃科诺莫(昏睡性脑炎与人脑皮质细胞结构学)、E. 波拉克(威尔逊病)、E. 甘珀(中脑研究对象)、J. 格斯特曼(格斯特曼 - 施特劳斯勒 - 申克综合征和格斯特曼顶叶综合征)、H. 霍夫与L. 舍恩鲍尔(脑肿瘤与外科手术)等的重要著作问世。主要的研究机构有维也纳医科大学医学院的第一和第二精神病学系(1870年成立,1911年合并,1971年分为神经学、精神病学以及儿童和青少年神经精神病学系)、维也纳的奥伯施泰纳研究所(1882年成立,1993年分离)、格拉茨和因斯布鲁克的大学系(均于1891年成立)以及其他实验室,在那里,像O. 马尔堡、H.霍夫、O. 珀茨尔、O. 考德斯、F. 塞特尔贝格尔、H. 察比切尔、K. 魏因加滕、H. 赖斯纳、W. 比尔克迈尔、H. 佩茨、F. 格斯滕布兰德、H. 伯恩海默、H. W. 海斯、H. 拉斯曼、W. 波韦、L. 德克等著名临床医生和神经科学家及其众多同事在现代神经科学的广泛领域做出了重要贡献。对未来具有重要意义的是维也纳医科大学脑研究所以及奥地利神经学会的成立,这将对奥地利神经科学研究的未来发展及其融入国际科学界产生进一步影响。

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