De Abreu Jorge, Borno Sonia, Montilla María, Dini Elizabeth
Centro de Atención Nutricional Infantil Antímano (CANIA), Caracas, Venezuela.
Arch Latinoam Nutr. 2005 Sep;55(3):226-34.
In order to determine the prevalence of anemia and the deficiency of vitamin A in children under 10 years, the concentration of hemoglobin, transferrin saturation, serum iron and the nutritional state of vitamin A were studied between 1999 and 2000, in 124 children with moderate malnutrition and 98 healthy children who attend triage consultation in the Centro de Atención Nutricional Infantil Antímano (CANIA, Caracas) by means of plasma retinol test (high performance liquid chromatography), relative dose response test (RDR) and conjunctival impression cytology (CIC). The dietary intake was analyzed by 24 hour recall. The Student t and Chi-square test were used for the statistical analysis of the data. The prevalence of vitamin A deficiency was approximately 10% in malnourished and healthy children, the CIC test discriminated a proportion of vitamin A deficient children superior to 25% and RDR test detected a significantly smaller percentage of deficiency in healthy children (p < 0.05). The prevalence of anemia was significantly higher in malnourished (34.2%) than in healthy children (19.2%). In children under 2 years the percentage of anemia reached 75.8% in undernourished children and 50% in healthy children. The consumption of macronutrients and micronutrients was inadequate; more than 40% undernourished children had caloric and macronutrients intake adequacy below 85%, whereas this level of adequacy in healthy children was around 30%. These results indicate there were problems of moderate anemia and moderate vitamin A deficiency in the studied infantile population, without significant differences between moderate undernourished and healthy children.
为了确定10岁以下儿童贫血和维生素A缺乏的患病率,1999年至2000年期间,通过血浆视黄醇检测(高效液相色谱法)、相对剂量反应试验(RDR)和结膜印迹细胞学检查(CIC),对124名中度营养不良儿童和98名在委内瑞拉加拉加斯儿童营养关注中心(CANIA)进行分诊咨询的健康儿童的血红蛋白浓度、转铁蛋白饱和度、血清铁以及维生素A营养状况进行了研究。通过24小时回顾法分析饮食摄入量。采用学生t检验和卡方检验对数据进行统计分析。营养不良儿童和健康儿童中维生素A缺乏的患病率约为10%,CIC试验鉴别出的维生素A缺乏儿童比例超过25%,而RDR试验检测出健康儿童中维生素A缺乏的比例明显较小(p<0.05)。营养不良儿童中贫血的患病率(34.2%)显著高于健康儿童(19.2%)。在2岁以下儿童中,营养不良儿童的贫血率达到75.8%,健康儿童为50%。宏量营养素和微量营养素的摄入量不足;超过40%的营养不良儿童热量和宏量营养素摄入量充足率低于85%,而健康儿童的这一充足率水平约为30%。这些结果表明,在所研究的婴幼儿群体中存在中度贫血和中度维生素A缺乏问题,中度营养不良儿童和健康儿童之间无显著差异。