促卵泡激素对未成熟小鼠睾丸体内蛋白质合成的刺激作用。

Stimulation of protein synthesis in vivo in immature mouse testis by FSH.

作者信息

Davies A G, Davies W E, Sumner C

出版信息

J Reprod Fertil. 1975 Mar;42(3):415-22. doi: 10.1530/jrf.0.0420415.

DOI:10.1530/jrf.0.0420415

Abstract

Human pituitary FSH was found to increase the incorporation of tritiated lysine into testicular protein in prepubertal mice in vivo. Radioactivity was measured in washed trichloracetic acid precipitates prepared from crude testicular homogenates. The time of maximum response was 8 to 16 hr after subcutaneous injection of the hormone. This was considerably later than the maximum response in vitro reported by other workers. Neither HCG nor dibutyryl cyclic 3',5'-adenosine monophosphate had a significant effect on the incorporation of lysine.

摘要

已发现人垂体促卵泡激素（FSH）能增加青春期前小鼠体内睾丸蛋白中氚标记赖氨酸的掺入量。放射性是在由睾丸粗匀浆制备的经洗涤的三氯乙酸沉淀物中测量的。皮下注射该激素后，最大反应时间为8至16小时。这比其他研究人员报道的体外最大反应时间要晚得多。人绒毛膜促性腺激素（HCG）和二丁酰环3',5'-单磷酸腺苷对赖氨酸的掺入均无显著影响。