Sakowitz O W, Harting I, Kohlhof P, Unterberg A W, Steiner H H
Department of Neurosurgery, University of Heidelberg, Germany.
Br J Neurosurg. 2005 Jun;19(3):260-4. doi: 10.1080/02688690500208734.
Low-grade (WHO level I) meningiomas are slow-growing, benign tumours typically presenting with unspecific symptoms (e.g. headache), seizures, cranial nerve compression and neuropsychological symptoms determined by location and size of the lesion. Haemorrhagic onset and sequelae are rare, and have been described infrequently. This is a case of a 50-year-old male presenting with signs of tentorial herniation secondary to hyperacute intratumoural haemorrhage (ITH) into a previously undiagnosed meningioma. Emergency surgical decompression and exstirpation of the lesion helped to achieve a favourable outcome. ITH has been described in all including benign intracranial neoplasms. Factors associated with a higher risk for haemorrhage in meningiomas are discussed. Though haemorrhages associated with meningiomas have been reported, ITH into low-grade meningiomas leading to herniation remains a rarity. Bearers of known lesions and their treating physicians who opt for conservative or delayed treatment should be aware of this remote complication.
低级别(世界卫生组织一级)脑膜瘤生长缓慢,为良性肿瘤,通常表现为非特异性症状(如头痛)、癫痫发作、颅神经受压以及由病变位置和大小决定的神经心理学症状。出血起病及其后遗症较为罕见,且鲜有相关描述。本文报道一例50岁男性患者,因超急性肿瘤内出血(ITH)进入先前未诊断出的脑膜瘤,继发小脑幕切迹疝。急诊手术减压并切除病变有助于取得良好预后。ITH可见于包括良性颅内肿瘤在内的所有肿瘤。文中讨论了与脑膜瘤出血风险较高相关的因素。尽管已有脑膜瘤相关出血的报道,但低级别脑膜瘤发生ITH导致疝形成仍属罕见。已知患有病变的患者及其选择保守或延迟治疗的主治医生应了解这种远期并发症。