Hayashi Kentaro, Takahata Hideaki, Nakamura Minoru, Iwasaki Keisuke
Department of Neurosurgery, Sasebo City General Hospital.
No Shinkei Geka. 2003 Dec;31(12):1309-13.
Brain tumors not uncommonly display a chronic course, with symptoms occurring insidiously. This case report describes a meningioma patient who presented sudden onset and rapidly progressing symptoms. She was 49 years old, a referred case from a nearby hospital, with severe headache and fever. This was also accompanied by unconsciousness and left hermiparesis which necessitated emergency brain CT and MRI scanning. A right temporal 5 cm ring enhancing lesion with massive surrounding edema was revealed. Despite osmotic diuretics to relieve brain edema, symptoms worsened, so decompressive right temporal craniotomy and total excision of the tumor was performed. This mass lesion was found to be extra axial, with histology revealing on atypical meningioma with massive necrosis. This rare case which is thought to be due to massive peritumoral edema, possibly from an ischemic occluded major feeder, conforms to glioma radiologically; while the clinical picture has a similarity to brain abscess. This case is presented as a reminder to neurosurgery practice that meningioma can also be a possibility when a ring enhancing cerebral mass in encountered and is accompanied by such a bizarre sudden and rapidly progressing neurologic condition.
脑肿瘤通常病程呈慢性,症状隐匿出现。本病例报告描述了一名脑膜瘤患者,其症状突然发作且迅速进展。患者49岁,系附近医院转诊而来,有严重头痛和发热症状。同时伴有昏迷和左侧偏瘫,因此需要进行紧急脑部CT和MRI扫描。检查发现右侧颞叶有一个5厘米的环形强化病灶,周围有大量水肿。尽管使用了渗透性利尿剂来减轻脑水肿,但症状仍恶化,于是进行了右侧颞叶减压开颅术并将肿瘤全部切除。发现该肿块位于脑外,组织学检查显示为非典型脑膜瘤伴大片坏死。这种罕见病例被认为是由于肿瘤周围大量水肿所致,可能是由于主要供血动脉缺血闭塞,在影像学上与胶质瘤相似;而临床表现与脑脓肿有相似之处。呈现此病例是为了提醒神经外科医生,当遇到环形强化的脑内肿块并伴有如此奇异的突然且迅速进展的神经症状时,脑膜瘤也应作为一种可能的诊断考虑。